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PDB: 10 results

4EO7
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Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
Descriptor: MAGNESIUM ION, Myeloid differentiation primary response protein MyD88
Authors:Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S.
Deposit date:2012-04-13
Release date:2013-04-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
4DOM
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Crystal Structure of the TIR-domain of Human Myeloid Differentiation Primary Response protein (MyD88)
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Jiang, J.S, Snyder, G.A, Xiao, T.
Deposit date:2012-02-09
Release date:2013-04-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
7L6W
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SFX structure of the MyD88 TIR domain higher-order assembly
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Flueckiger, L, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Stacey, K.J, Darmanin, C, Kobe, B, Xu, H, Ve, T.
Deposit date:2020-12-24
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
7BER
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SFX structure of the MyD88 TIR domain higher-order assembly (solved, rebuilt and refined using an identical protocol to the MicroED structure of the MyD88 TIR domain higher-order assembly)
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T.
Deposit date:2020-12-24
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
7BEQ
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MicroED structure of the MyD88 TIR domain higher-order assembly
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T.
Deposit date:2020-12-24
Release date:2021-03-10
Last modified:2024-01-31
Method:ELECTRON CRYSTALLOGRAPHY (3 Å)
Cite:MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
6I3N
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BU of 6i3n by Molmil
Helical MyD88 death domain filament
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Moncrieffe, M.C, Bollschweiler, D, Penczek, P.A.P, Gay, N.J.
Deposit date:2018-11-06
Release date:2019-11-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling.
Structure, 28, 2020
8W8M
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Cryo-EM structure of helical filament of MyD88 TIR
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Kasai, K, Imamura, K, Narita, A, Makino, F, Miyata, T, Kato, T, Namba, K, Onishi, H, Tochio, H.
Deposit date:2023-09-04
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Signaling adopter protein in a self-assembled form
To Be Published
3MOP
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The ternary Death Domain complex of MyD88, IRAK4, and IRAK2
Descriptor: Interleukin-1 receptor-associated kinase 4, Interleukin-1 receptor-associated kinase-like 2, Myeloid differentiation primary response protein MyD88
Authors:Lin, S.-C, Lo, Y.-C, Wu, H.
Deposit date:2010-04-23
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.
Nature, 465, 2010
2JS7
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Solution NMR structure of human myeloid differentiation primary response (MyD88). Northeast Structural Genomics target HR2869A
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Rossi, P, Ramelot, T.A, Tao, X, Ciano, M, Ho, C, Ma, L.-C, Xiao, R, Acton, T.B, Kennedy, M.A, Tong, L, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-29
Release date:2007-10-23
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Solution NMR Structure of Human Myeloid Differentiation Primary Response (MyD88).
To be Published
2Z5V
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Solution structure of the TIR domain of human MyD88
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Ohnishi, H, Tochio, H, Hiroaki, H, Kondo, N, Kato, Z, Shirakawa, M.
Deposit date:2007-07-19
Release date:2008-08-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.
Proc.Natl.Acad.Sci.USA, 2009

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