6PEW
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6PEV
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3WX4
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6E10
| PTEX Core Complex in the Engaged (Extended) State | Descriptor: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | Authors: | Ho, C, Lai, M, Zhou, Z.H. | Deposit date: | 2018-07-08 | Release date: | 2018-08-22 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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6E11
| PTEX Core Complex in the Resetting (Compact) State | Descriptor: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | Authors: | Ho, C, Lai, M, Zhou, Z.H. | Deposit date: | 2018-07-08 | Release date: | 2018-08-22 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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7D20
| Cryo-EM structure of SET8-CENP-A-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | Deposit date: | 2020-09-15 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. Life Sci Alliance, 4, 2021
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7D1Z
| Cryo-EM structure of SET8-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | Deposit date: | 2020-09-15 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. Life Sci Alliance, 4, 2021
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1S68
| Structure and Mechanism of RNA Ligase | Descriptor: | ADENOSINE MONOPHOSPHATE, RNA Ligase 2 | Authors: | Ho, C.K, Wang, L.K, Lima, C.D, Shuman, S. | Deposit date: | 2004-01-22 | Release date: | 2004-02-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of RNA ligase. Structure, 12, 2004
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4PDS
| Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53 | Authors: | Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F. | Deposit date: | 2014-04-21 | Release date: | 2014-05-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of Rad53 kinase activation by dimerization and activation segment exchange. Cell Signal., 26, 2014
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7MRW
| Native RhopH complex of the malaria parasite Plasmodium falciparum | Descriptor: | Cytoadherence linked asexual protein 3.1, High molecular weight rhoptry protein 2, High molecular weight rhoptry protein 3 | Authors: | Ho, C.M, Jih, J, Lai, M, Li, X.R, Goldberg, D.E, Beck, J.R, Zhou, Z.H. | Deposit date: | 2021-05-10 | Release date: | 2021-09-15 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Native structure of the RhopH complex, a key determinant of malaria parasite nutrient acquisition. Proc.Natl.Acad.Sci.USA, 118, 2021
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3KB2
| Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256 | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, SPBc2 prophage-derived uncharacterized protein yorR | Authors: | Forouhar, F, Friedman, D, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Ho, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-20 | Release date: | 2009-10-27 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Northeast Structural Genomics Consortium Target SR256 To be Published
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4LLD
| Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A | Descriptor: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | Authors: | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | Deposit date: | 2013-07-09 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLM
| Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 1, CRD1) at 1.75A | Descriptor: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | Authors: | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | Deposit date: | 2013-07-09 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLY
| Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A | Descriptor: | GLYCEROL, MAGNESIUM ION, light chain Clambda, ... | Authors: | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | Deposit date: | 2013-07-09 | Release date: | 2014-01-29 | Last modified: | 2019-06-26 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLU
| Structure of Pertuzumab Fab with light chain Clambda at 2.16A | Descriptor: | ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ... | Authors: | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | Deposit date: | 2013-07-09 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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4LLQ
| Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 2 beta, CRD2b) at 1.42A | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, mutated CH1, mutated light chain Clambda | Authors: | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | Deposit date: | 2013-07-09 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
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2KEW
| The solution structure of Bacillus subtilis SR211 START domain by NMR spectroscopy | Descriptor: | Uncharacterized protein yndB | Authors: | Mercier, K.A, Mueller, G.A, Powers, R, Acton, T.B, Ciano, M, Ho, C, Lui, J, Ma, L, Rost, B, Rossi, R, Xiao, R, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-02-05 | Release date: | 2009-03-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | (1)H, (13)C, and (15)N NMR assignments for the Bacillus subtilis yndB START domain. Biomol.Nmr Assign., 3, 2009
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1RVW
| R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY | Descriptor: | CARBON MONOXIDE, HEMOGLOBIN, PHOSPHATE ION, ... | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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3HD6
| Crystal Structure of the Human Rhesus Glycoprotein RhCG | Descriptor: | Ammonium transporter Rh type C, octyl beta-D-glucopyranoside | Authors: | Gruswitz, F, Chaudhary, S, Ho, J.D, Pezeshki, B, Ho, C.-M, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2009-05-06 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Function of human Rh based on structure of RhCG at 2.1 A. Proc.Natl.Acad.Sci.USA, 107, 2010
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1VWT
| T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY | Descriptor: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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2KTE
| The solution structure of Bacillus subtilis, YndB, Northeast Structural Genomics Consoritum Target SR211 | Descriptor: | Uncharacterized protein yndB | Authors: | Mercier, K.A, Mueller, G.A, Powers, R, Acton, T.B, Ciano, M, Ho, C, Lui, J, Ma, L, Rost, B, Rossi, R, Montelione, G.T, Xiao, R, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-29 | Release date: | 2010-06-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis. Proteins, 78, 2010
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8TPU
| Subtomogram averaged consensus structure of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Anton, L, Cheng, W, Zhu, X, Ho, C.M. | Deposit date: | 2023-08-05 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Divergent translational landscape reflects adaptation to biased codon usage in malaria parasites To Be Published
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4CCL
| X-Ray structure of E. coli ycfD | Descriptor: | 50S RIBOSOMAL PROTEIN L16 ARGININE HYDROXYLASE, MANGANESE (II) ION, SULFATE ION | Authors: | McDonough, M.A, Ho, C.H, Kershaw, N.J, Schofield, C.J. | Deposit date: | 2013-10-23 | Release date: | 2014-04-30 | Last modified: | 2020-06-03 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014
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2FFG
| Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360. | Descriptor: | ykuJ | Authors: | Kuzin, A.P, Abashidze, M, Forouhar, F, Vorobiev, S.M, Ho, C.K, Janjua, H, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-12-19 | Release date: | 2005-12-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360. To be Published
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2BDR
| Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49 | Descriptor: | SODIUM ION, Ureidoglycolate hydrolase | Authors: | Forouhar, F, Abashidze, M, Jayaraman, S, Ho, C.K, Conover, K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-10-20 | Release date: | 2005-11-15 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49 To be Published
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