4PDS

Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP

Summary for 4PDS

Entry DOI	10.2210/pdb4pds/pdb
Related	4PDP
Descriptor	Serine/threonine-protein kinase RAD53, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywords	kinase domain, anp, c-lobe, activation segment exchange, transferase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	2
Total formula weight	77865.72
Authors	Ho, C.S.,Wybenga-Groot, L.E.,Ceccarelli, D.F.,Sicheri, F. (deposition date: 2014-04-21, release date: 2014-05-28, Last modification date: 2023-09-27)
Primary citation	Wybenga-Groot, L.E.,Ho, C.S.,Sweeney, F.D.,Ceccarelli, D.F.,McGlade, C.J.,Durocher, D.,Sicheri, F. Structural basis of Rad53 kinase activation by dimerization and activation segment exchange. Cell Signal., 26:1825-1836, 2014 Cited by PubMed: 24815189 DOI: 10.1016/j.cellsig.2014.05.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation