4PDS

Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine/threonine-protein kinase RAD53	polymer	347	38426.7	2	UniProt (P22216) Pfam (PF00069) In PDB	Saccharomyces cerevisiae (Baker's yeast)	CHEK2 homolog,Serine-protein kinase 1
2	A, B	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)

Sequence modifications

A, B: 170 - 512 (UniProt: P22216)

PDB	External Database	Details
Gly 166	-	expression tag
Ala 167	-	expression tag
Met 168	-	expression tag
Ala 169	-	expression tag
Ser 225	Ala 225	engineered mutation
Ala 339	Asp 339	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76853.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1012.4
All*	Total formula weight	77865.7

*Water molecules are not included.