8W8M

Cryo-EM structure of helical filament of MyD88 TIR

This is a non-PDB format compatible entry.

Summary for 8W8M

• Entry DOI: 10.2210/pdb8w8m/pdb
• EMDB information: 37355
• Descriptor: Myeloid differentiation primary response protein MyD88 (1 entity in total)
• Functional Keywords: signaling protein, innate immunity, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 102
• Total formula weight: 1717861.05

Authors

Kasai, K.,Imamura, K.,Narita, A.,Makino, F.,Miyata, T.,Kato, T.,Namba, K.,Onishi, H.,Tochio, H. (deposition date: 2023-09-04, release date: 2024-09-04, Last modification date: 2025-03-26)

• Primary citation: Kasai, K.,Imamura, K.,Uno, M.,Sekiyama, N.,Miyata, T.,Makino, F.,Yamada, R.,Takahashi, Y.,Kodera, N.,Namba, K.,Ohnishi, H.,Narita, A.,Konno, H.,Tochio, H.; From Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling; Biorxiv, 2024; DOI: 10.1101/2024.09.13.612588

Experimental method

ELECTRON MICROSCOPY (3.28 Å)