6I3N

Helical MyD88 death domain filament

Summary for 6I3N

Entry DOI	10.2210/pdb6i3n/pdb
EMDB information	4405
Descriptor	Myeloid differentiation primary response protein MyD88 (1 entity in total)
Functional Keywords	helix, filament, tlr, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	13
Total formula weight	229409.35
Authors	Moncrieffe, M.C.,Bollschweiler, D.,Penczek, P.A.P.,Gay, N.J. (deposition date: 2018-11-06, release date: 2019-11-20, Last modification date: 2020-03-11)
Primary citation	Moncrieffe, M.C.,Bollschweiler, D.,Li, B.,Penczek, P.A.,Hopkins, L.,Bryant, C.E.,Klenerman, D.,Gay, N.J. MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling. Structure, 28:281-289.e3, 2020 Cited by PubMed: 31995744 DOI: 10.1016/j.str.2020.01.003 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation