4TXW
 
 | | Crystal structure of CBM32-4 from the Clostridium perfringens NagH | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Hyaluronoglucosaminidase | | Authors: | Grondin, J.M, Ficko-Blean, E, Boraston, A.B, Smith, S.P. | | Deposit date: | 2014-07-07 | | Release date: | 2015-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Solution Structure and Dynamics of Full-length GH84A, a multimodular B-N-acetylglucosaminidase from Clostridium perfringens
To Be Published
|
|
2LS6
 | | Solution NMR Structure of a Non-canonical galactose-binding CBM32 from Clostridium perfringens | | Descriptor: | Hyaluronoglucosaminidase | | Authors: | Grondin, J.M, Chitayat, S, Ficko-Blean, E, Boraston, A.B, Smith, S.P. | | Deposit date: | 2012-04-20 | | Release date: | 2013-05-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | An unusual mode of galactose recognition by a family 32 carbohydrate-binding module.
J.Mol.Biol., 426, 2014
|
|
7S0P
 | | Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine | | Descriptor: | Coagulation factor VIII, PHOSPHOSERINE | | Authors: | Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. | | Deposit date: | 2021-08-30 | | Release date: | 2021-10-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.
Front Mol Biosci, 9, 2022
|
|
8PFE
 | |
4XZU
 | |
6OE2
 | |
9EOU
 | |
7P5U
 | |
3NNG
 | | Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR258E | | Descriptor: | CALCIUM ION, uncharacterized protein | | Authors: | Vorobiev, S, Su, M, Dimaio, F, Baker, D, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Foote, E.L, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-23 | | Release date: | 2010-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.177 Å) | | Cite: | Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis.
To be Published
|
|
5Y4M
 | | Discoidin domain of human CASPR2 | | Descriptor: | 1,2-ETHANEDIOL, human CASPR2 Disc domain | | Authors: | Liu, H, Xu, F, Zhang, J, Liang, W. | | Deposit date: | 2017-08-04 | | Release date: | 2018-08-08 | | Last modified: | 2019-02-20 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition.
J. Autoimmun., 96, 2019
|
|
7RGA
 | | Crystal structure of nanoCLAMP3:VHH in complex with MTX | | Descriptor: | METHOTREXATE, SODIUM ION, nano CLostridial Antibody Mimetic Protein 3 VHH | | Authors: | Guo, Z, Alexandrov, K. | | Deposit date: | 2021-07-14 | | Release date: | 2022-05-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices.
Nat Commun, 12, 2021
|
|
5DQ0
 | | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | | Authors: | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | | Deposit date: | 2015-09-14 | | Release date: | 2016-09-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site
To Be Published
|
|
1XPW
 | | Solution NMR Structure of human protein HSPCO34. Northeast Structural Genomics Target HR1958 | | Descriptor: | LOC51668 protein | | Authors: | Ramelot, T.A, Xiao, R, Ma, L.C, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-10-09 | | Release date: | 2004-11-09 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
|
|
2Z4F
 | | Solution structure of the Discoidin Domain of DDR2 | | Descriptor: | Discoidin domain-containing receptor 2 | | Authors: | Ichikawa, O, Osawa, M, Nishida, N, Goshima, N, Nomura, N, Shimada, I. | | Deposit date: | 2007-06-16 | | Release date: | 2007-09-04 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Structural basis of the collagen-binding mode of discoidin domain receptor 2
Embo J., 26, 2007
|
|
1IQD
 | | Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. | | Descriptor: | HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN | | Authors: | Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P. | | Deposit date: | 2001-07-21 | | Release date: | 2001-08-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII.
Blood, 98, 2001
|
|
7O1N
 | |
1TVG
 | | X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958. | | Descriptor: | CALCIUM ION, LOC51668 protein, SAMARIUM (III) ION | | Authors: | Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-06-29 | | Release date: | 2004-11-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
|
|
6FMF
 | | Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure | | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid | | Authors: | Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. | | Deposit date: | 2018-01-31 | | Release date: | 2018-10-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.811 Å) | | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
|
|
1KEX
 | | Crystal Structure of the b1 Domain of Human Neuropilin-1 | | Descriptor: | Neuropilin-1 | | Authors: | Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G. | | Deposit date: | 2001-11-18 | | Release date: | 2003-01-28 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
|
|
6FMC
 | | Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | | Authors: | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | | Deposit date: | 2018-01-30 | | Release date: | 2018-10-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (0.9 Å) | | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
|
|
3BN6
 | | Crystal Structure of the C2 Domain of Bovine Lactadherin at 1.67 Angstrom Resolution | | Descriptor: | Lactadherin | | Authors: | Shao, C, Novakovic, V.A, Head, J.F, Seaton, B.A, Gilbert, G.E. | | Deposit date: | 2007-12-13 | | Release date: | 2007-12-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.
J.Biol.Chem., 283, 2008
|
|
3F2Z
 | | Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B | | Descriptor: | uncharacterized protein BF3579 | | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Janjua, H, Xiao, R, Foote, E.L, Ciccosanti, C, Lee, D, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-10-30 | | Release date: | 2008-11-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B
To be Published
|
|
5N6W
 | | Retinoschisin R141H Mutant | | Descriptor: | Retinoschisin | | Authors: | Ramsay, E.P, Collins, R.F, Owens, T.W, Siebert, C.A, Jones, R.P.O, Roseman, A, Wang, T, Baldock, C. | | Deposit date: | 2017-02-16 | | Release date: | 2017-04-12 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function
Human Molecular Genetics, 25, 2016
|
|
7D2A
 | | CBM32 of AlyQ in complex with 4,5-unsaturated mannuronic acid | | Descriptor: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, AlyQ, CALCIUM ION, ... | | Authors: | Teh, A.H, Sim, P.F. | | Deposit date: | 2020-09-16 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Structural basis for binding uronic acids by family 32 carbohydrate-binding modules.
Biochem.Biophys.Res.Commun., 533, 2020
|
|
7D29
 | | CBM32 of AlyQ | | Descriptor: | AlyQ, CALCIUM ION | | Authors: | Teh, A.H, Sim, P.F. | | Deposit date: | 2020-09-16 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for binding uronic acids by family 32 carbohydrate-binding modules.
Biochem.Biophys.Res.Commun., 533, 2020
|
|
