7RGA

Crystal structure of nanoCLAMP3:VHH in complex with MTX

Summary for 7RGA

• Entry DOI: 10.2210/pdb7rga/pdb
• Descriptor: nano CLostridial Antibody Mimetic Protein 3 VHH, METHOTREXATE, SODIUM ION, ... (4 entities in total)
• Functional Keywords: immune system
• Biological source: synthetic construct
• Total number of polymer chains: 7
• Total formula weight: 232000.16

Authors

Guo, Z.,Alexandrov, K. (deposition date: 2021-07-14, release date: 2022-05-25, Last modification date: 2023-10-18)

• Primary citation: Guo, Z.,Smutok, O.,Johnston, W.A.,Walden, P.,Ungerer, J.P.J.,Peat, T.S.,Newman, J.,Parker, J.,Nebl, T.,Hepburn, C.,Melman, A.,Suderman, R.J.,Katz, E.,Alexandrov, K.; Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices.; Nat Commun, 12:7137-7137, 2021; PubMed: 34880210; DOI: 10.1038/s41467-021-27184-w

Experimental method

X-RAY DIFFRACTION (2.9 Å)