4XZU

Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody

Summary for 4XZU

Entry DOI	10.2210/pdb4xzu/pdb
Descriptor	3E6 antibody Fab heavy chain, 3E6 antibody Fab light chain, Coagulation factor VIII, ... (5 entities in total)
Functional Keywords	immunoglobulin, blood coagulation, antibody, discoidin, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	128785.09
Authors	Spiegel, P.C.,Wuerth, M.E. (deposition date: 2015-02-05, release date: 2015-12-09, Last modification date: 2019-12-04)
Primary citation	Wuerth, M.E.,Cragerud, R.K.,Clint Spiegel, P. Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody. Sci Rep, 5:17216-17216, 2015 Cited by PubMed: 26598467 DOI: 10.1038/srep17216 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation