4XZU
Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, E) | 3E6 antibody Fab heavy chain | polymer | 219 | 23538.4 | 2 | Mus musculus | ||
| 2 | B, E (B, F) | 3E6 antibody Fab light chain | polymer | 213 | 23288.7 | 2 | Mus musculus | ||
| 3 | C, F (M, G) | Coagulation factor VIII | polymer | 154 | 17529.1 | 2 | UniProt (P00451) Pfam (PF00754) | Homo sapiens (Human) | Antihemophilic factor,AHF,Procoagulant component |
| 4 | G, H, I (A, M, F) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | J, K, L, M, N... (A, B, M, E, F...) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 128712.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 72.9 | |
| All* | Total formula weight | 128785.1 |
