5N6W

Retinoschisin R141H Mutant

Summary for 5N6W

Entry DOI	10.2210/pdb5n6w/pdb
EMDB information	3595
Descriptor	Retinoschisin (1 entity in total)
Functional Keywords	retinoschisin discoidin domain retinal structure, structural protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted : O15537
Total number of polymer chains	16
Total formula weight	368670.43
Authors	Ramsay, E.P.,Collins, R.F.,Owens, T.W.,Siebert, C.A.,Jones, R.P.O.,Roseman, A.,Wang, T.,Baldock, C. (deposition date: 2017-02-16, release date: 2017-04-12, Last modification date: 2017-08-30)
Primary citation	Ramsay, E.P.,Collins, R.F.,Owens, T.W.,Siebert, C.A.,Jones, R.P.O.,Roseman, A.,Baldock, C. Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function Human Molecular Genetics, 25:5311-5320, 2016 Cited by PubMed: 27798099 DOI: 10.1093/hmg/ddw345 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation