5N6W

Retinoschisin R141H Mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001654	biological_process	eye development
A	0001786	molecular_function	phosphatidylserine binding
A	0001917	cellular_component	photoreceptor inner segment
A	0005543	molecular_function	phospholipid binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0007155	biological_process	cell adhesion
A	0007601	biological_process	visual perception
A	0008289	molecular_function	lipid binding
A	0009897	cellular_component	external side of plasma membrane
A	0009986	cellular_component	cell surface
A	0010842	biological_process	retina layer formation
A	0032991	cellular_component	protein-containing complex
A	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
A	0044877	molecular_function	protein-containing complex binding
A	0051260	biological_process	protein homooligomerization
A	0098984	cellular_component	neuron to neuron synapse
B	0001654	biological_process	eye development
B	0001786	molecular_function	phosphatidylserine binding
B	0001917	cellular_component	photoreceptor inner segment
B	0005543	molecular_function	phospholipid binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0007155	biological_process	cell adhesion
B	0007601	biological_process	visual perception
B	0008289	molecular_function	lipid binding
B	0009897	cellular_component	external side of plasma membrane
B	0009986	cellular_component	cell surface
B	0010842	biological_process	retina layer formation
B	0032991	cellular_component	protein-containing complex
B	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
B	0044877	molecular_function	protein-containing complex binding
B	0051260	biological_process	protein homooligomerization
B	0098984	cellular_component	neuron to neuron synapse
C	0001654	biological_process	eye development
C	0001786	molecular_function	phosphatidylserine binding
C	0001917	cellular_component	photoreceptor inner segment
C	0005543	molecular_function	phospholipid binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005886	cellular_component	plasma membrane
C	0007155	biological_process	cell adhesion
C	0007601	biological_process	visual perception
C	0008289	molecular_function	lipid binding
C	0009897	cellular_component	external side of plasma membrane
C	0009986	cellular_component	cell surface
C	0010842	biological_process	retina layer formation
C	0032991	cellular_component	protein-containing complex
C	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
C	0044877	molecular_function	protein-containing complex binding
C	0051260	biological_process	protein homooligomerization
C	0098984	cellular_component	neuron to neuron synapse
D	0001654	biological_process	eye development
D	0001786	molecular_function	phosphatidylserine binding
D	0001917	cellular_component	photoreceptor inner segment
D	0005543	molecular_function	phospholipid binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005886	cellular_component	plasma membrane
D	0007155	biological_process	cell adhesion
D	0007601	biological_process	visual perception
D	0008289	molecular_function	lipid binding
D	0009897	cellular_component	external side of plasma membrane
D	0009986	cellular_component	cell surface
D	0010842	biological_process	retina layer formation
D	0032991	cellular_component	protein-containing complex
D	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
D	0044877	molecular_function	protein-containing complex binding
D	0051260	biological_process	protein homooligomerization
D	0098984	cellular_component	neuron to neuron synapse
E	0001654	biological_process	eye development
E	0001786	molecular_function	phosphatidylserine binding
E	0001917	cellular_component	photoreceptor inner segment
E	0005543	molecular_function	phospholipid binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005886	cellular_component	plasma membrane
E	0007155	biological_process	cell adhesion
E	0007601	biological_process	visual perception
E	0008289	molecular_function	lipid binding
E	0009897	cellular_component	external side of plasma membrane
E	0009986	cellular_component	cell surface
E	0010842	biological_process	retina layer formation
E	0032991	cellular_component	protein-containing complex
E	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
E	0044877	molecular_function	protein-containing complex binding
E	0051260	biological_process	protein homooligomerization
E	0098984	cellular_component	neuron to neuron synapse
F	0001654	biological_process	eye development
F	0001786	molecular_function	phosphatidylserine binding
F	0001917	cellular_component	photoreceptor inner segment
F	0005543	molecular_function	phospholipid binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005886	cellular_component	plasma membrane
F	0007155	biological_process	cell adhesion
F	0007601	biological_process	visual perception
F	0008289	molecular_function	lipid binding
F	0009897	cellular_component	external side of plasma membrane
F	0009986	cellular_component	cell surface
F	0010842	biological_process	retina layer formation
F	0032991	cellular_component	protein-containing complex
F	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
F	0044877	molecular_function	protein-containing complex binding
F	0051260	biological_process	protein homooligomerization
F	0098984	cellular_component	neuron to neuron synapse
G	0001654	biological_process	eye development
G	0001786	molecular_function	phosphatidylserine binding
G	0001917	cellular_component	photoreceptor inner segment
G	0005543	molecular_function	phospholipid binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0005886	cellular_component	plasma membrane
G	0007155	biological_process	cell adhesion
G	0007601	biological_process	visual perception
G	0008289	molecular_function	lipid binding
G	0009897	cellular_component	external side of plasma membrane
G	0009986	cellular_component	cell surface
G	0010842	biological_process	retina layer formation
G	0032991	cellular_component	protein-containing complex
G	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
G	0044877	molecular_function	protein-containing complex binding
G	0051260	biological_process	protein homooligomerization
G	0098984	cellular_component	neuron to neuron synapse
H	0001654	biological_process	eye development
H	0001786	molecular_function	phosphatidylserine binding
H	0001917	cellular_component	photoreceptor inner segment
H	0005543	molecular_function	phospholipid binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0005886	cellular_component	plasma membrane
H	0007155	biological_process	cell adhesion
H	0007601	biological_process	visual perception
H	0008289	molecular_function	lipid binding
H	0009897	cellular_component	external side of plasma membrane
H	0009986	cellular_component	cell surface
H	0010842	biological_process	retina layer formation
H	0032991	cellular_component	protein-containing complex
H	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
H	0044877	molecular_function	protein-containing complex binding
H	0051260	biological_process	protein homooligomerization
H	0098984	cellular_component	neuron to neuron synapse
I	0001654	biological_process	eye development
I	0001786	molecular_function	phosphatidylserine binding
I	0001917	cellular_component	photoreceptor inner segment
I	0005543	molecular_function	phospholipid binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0005886	cellular_component	plasma membrane
I	0007155	biological_process	cell adhesion
I	0007601	biological_process	visual perception
I	0008289	molecular_function	lipid binding
I	0009897	cellular_component	external side of plasma membrane
I	0009986	cellular_component	cell surface
I	0010842	biological_process	retina layer formation
I	0032991	cellular_component	protein-containing complex
I	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
I	0044877	molecular_function	protein-containing complex binding
I	0051260	biological_process	protein homooligomerization
I	0098984	cellular_component	neuron to neuron synapse
J	0001654	biological_process	eye development
J	0001786	molecular_function	phosphatidylserine binding
J	0001917	cellular_component	photoreceptor inner segment
J	0005543	molecular_function	phospholipid binding
J	0005576	cellular_component	extracellular region
J	0005615	cellular_component	extracellular space
J	0005886	cellular_component	plasma membrane
J	0007155	biological_process	cell adhesion
J	0007601	biological_process	visual perception
J	0008289	molecular_function	lipid binding
J	0009897	cellular_component	external side of plasma membrane
J	0009986	cellular_component	cell surface
J	0010842	biological_process	retina layer formation
J	0032991	cellular_component	protein-containing complex
J	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
J	0044877	molecular_function	protein-containing complex binding
J	0051260	biological_process	protein homooligomerization
J	0098984	cellular_component	neuron to neuron synapse
K	0001654	biological_process	eye development
K	0001786	molecular_function	phosphatidylserine binding
K	0001917	cellular_component	photoreceptor inner segment
K	0005543	molecular_function	phospholipid binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0005886	cellular_component	plasma membrane
K	0007155	biological_process	cell adhesion
K	0007601	biological_process	visual perception
K	0008289	molecular_function	lipid binding
K	0009897	cellular_component	external side of plasma membrane
K	0009986	cellular_component	cell surface
K	0010842	biological_process	retina layer formation
K	0032991	cellular_component	protein-containing complex
K	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
K	0044877	molecular_function	protein-containing complex binding
K	0051260	biological_process	protein homooligomerization
K	0098984	cellular_component	neuron to neuron synapse
L	0001654	biological_process	eye development
L	0001786	molecular_function	phosphatidylserine binding
L	0001917	cellular_component	photoreceptor inner segment
L	0005543	molecular_function	phospholipid binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0007155	biological_process	cell adhesion
L	0007601	biological_process	visual perception
L	0008289	molecular_function	lipid binding
L	0009897	cellular_component	external side of plasma membrane
L	0009986	cellular_component	cell surface
L	0010842	biological_process	retina layer formation
L	0032991	cellular_component	protein-containing complex
L	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
L	0044877	molecular_function	protein-containing complex binding
L	0051260	biological_process	protein homooligomerization
L	0098984	cellular_component	neuron to neuron synapse
M	0001654	biological_process	eye development
M	0001786	molecular_function	phosphatidylserine binding
M	0001917	cellular_component	photoreceptor inner segment
M	0005543	molecular_function	phospholipid binding
M	0005576	cellular_component	extracellular region
M	0005615	cellular_component	extracellular space
M	0005886	cellular_component	plasma membrane
M	0007155	biological_process	cell adhesion
M	0007601	biological_process	visual perception
M	0008289	molecular_function	lipid binding
M	0009897	cellular_component	external side of plasma membrane
M	0009986	cellular_component	cell surface
M	0010842	biological_process	retina layer formation
M	0032991	cellular_component	protein-containing complex
M	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
M	0044877	molecular_function	protein-containing complex binding
M	0051260	biological_process	protein homooligomerization
M	0098984	cellular_component	neuron to neuron synapse
N	0001654	biological_process	eye development
N	0001786	molecular_function	phosphatidylserine binding
N	0001917	cellular_component	photoreceptor inner segment
N	0005543	molecular_function	phospholipid binding
N	0005576	cellular_component	extracellular region
N	0005615	cellular_component	extracellular space
N	0005886	cellular_component	plasma membrane
N	0007155	biological_process	cell adhesion
N	0007601	biological_process	visual perception
N	0008289	molecular_function	lipid binding
N	0009897	cellular_component	external side of plasma membrane
N	0009986	cellular_component	cell surface
N	0010842	biological_process	retina layer formation
N	0032991	cellular_component	protein-containing complex
N	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
N	0044877	molecular_function	protein-containing complex binding
N	0051260	biological_process	protein homooligomerization
N	0098984	cellular_component	neuron to neuron synapse
O	0001654	biological_process	eye development
O	0001786	molecular_function	phosphatidylserine binding
O	0001917	cellular_component	photoreceptor inner segment
O	0005543	molecular_function	phospholipid binding
O	0005576	cellular_component	extracellular region
O	0005615	cellular_component	extracellular space
O	0005886	cellular_component	plasma membrane
O	0007155	biological_process	cell adhesion
O	0007601	biological_process	visual perception
O	0008289	molecular_function	lipid binding
O	0009897	cellular_component	external side of plasma membrane
O	0009986	cellular_component	cell surface
O	0010842	biological_process	retina layer formation
O	0032991	cellular_component	protein-containing complex
O	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
O	0044877	molecular_function	protein-containing complex binding
O	0051260	biological_process	protein homooligomerization
O	0098984	cellular_component	neuron to neuron synapse
P	0001654	biological_process	eye development
P	0001786	molecular_function	phosphatidylserine binding
P	0001917	cellular_component	photoreceptor inner segment
P	0005543	molecular_function	phospholipid binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0005886	cellular_component	plasma membrane
P	0007155	biological_process	cell adhesion
P	0007601	biological_process	visual perception
P	0008289	molecular_function	lipid binding
P	0009897	cellular_component	external side of plasma membrane
P	0009986	cellular_component	cell surface
P	0010842	biological_process	retina layer formation
P	0032991	cellular_component	protein-containing complex
P	0043325	molecular_function	phosphatidylinositol-3,4-bisphosphate binding
P	0044877	molecular_function	protein-containing complex binding
P	0051260	biological_process	protein homooligomerization
P	0098984	cellular_component	neuron to neuron synapse

Functional Information from PROSITE/UniProt

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. AWlskfqdssq......WLqIDlkeikvIsgIlTQG

Chain	Residue	Details
A	ALA111-GLY140

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2496
Details	Domain: {"description":"F5/8 type C","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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