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PDB: 8 results

7Z1X
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BU of 7z1x by Molmil
Crystal structure of human Gasdermin D complexed with nanobodies VHH-2 and VHH-6
Descriptor: Gasdermin-D, VHH-2, VHH-6
Authors:Kopp, A, Hagelueken, G, Geyer, M.
Deposit date:2022-02-25
Release date:2023-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Pyroptosis inhibiting nanobodies block Gasdermin D pore formation.
Nat Commun, 14, 2023
5NH1
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BU of 5nh1 by Molmil
Structure of the C-terminal domain of human Gasdermin D
Descriptor: Gasdermin-D
Authors:Anton, L, Sborgi, L, Hiller, S, Broz, P, Maier, T.
Deposit date:2017-03-21
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Insights into Gasdermin D activation from the crystal structure of its C-terminal domain
Biorxiv, 2017
5WQT
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BU of 5wqt by Molmil
Structure of a protein involved in pyroptosis
Descriptor: CITRIC ACID, GLYCEROL, Gasdermin-D
Authors:Kuang, S, Li, J.
Deposit date:2016-11-28
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6KN0
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BU of 6kn0 by Molmil
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
Descriptor: Caspase-1, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-02
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.793 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6AO4
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BU of 6ao4 by Molmil
Crystal structure of the human gasdermin D C-terminal domain
Descriptor: Gasdermin-D
Authors:Liu, Z, Wang, C, Yang, J, Xiao, T.S.
Deposit date:2017-08-15
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Structure, 26, 2018
6N9O
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BU of 6n9o by Molmil
Crystal structure of human GSDMD
Descriptor: Gasdermin-D
Authors:Liu, Z, Wang, C, Yang, J, Xiao, T.S.
Deposit date:2018-12-03
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 51, 2019
6KMZ
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BU of 6kmz by Molmil
caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
Descriptor: Caspase-4, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6VFE
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BU of 6vfe by Molmil
Gasdermin D pore
Descriptor: Gasdermin-D, N-terminal
Authors:Xia, S, Ruan, J, Wu, H.
Deposit date:2020-01-03
Release date:2021-04-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Nature, 593, 2021

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