5NH1

Structure of the C-terminal domain of human Gasdermin D

Summary for 5NH1

• Entry DOI: 10.2210/pdb5nh1/pdb
• Descriptor: Gasdermin-D (2 entities in total)
• Functional Keywords: apoptosis, gasdermin, pyroptosis, inflammasome, innate immunity, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Gasdermin-D: Cytoplasm, cytosol . Gasdermin-D, N-terminal: Cell membrane : P57764
• Total number of polymer chains: 1
• Total formula weight: 22168.23

Authors

Anton, L.,Sborgi, L.,Hiller, S.,Broz, P.,Maier, T. (deposition date: 2017-03-21, release date: 2017-09-20, Last modification date: 2024-01-17)

• Primary citation: Anton, L.,Sborgi, L.,Hiller, S.,Broz, P.,Maier, T.; Insights into Gasdermin D activation from the crystal structure of its C-terminal domain; Biorxiv, 2017; DOI: 10.1101/187211

Experimental method

X-RAY DIFFRACTION (2.04 Å)