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5WQT

Structure of a protein involved in pyroptosis

Summary for 5WQT
Entry DOI10.2210/pdb5wqt/pdb
DescriptorGasdermin-D, GLYCEROL, CITRIC ACID, ... (4 entities in total)
Functional Keywordspyrtosis, signaling protein
Biological sourceHomo sapiens (Human)
Cellular locationGasdermin-D: Cytoplasm, cytosol . Gasdermin-D, N-terminal: Cell membrane : P57764
Total number of polymer chains2
Total formula weight45684.52
Authors
Kuang, S.,Li, J. (deposition date: 2016-11-28, release date: 2017-10-04, Last modification date: 2023-11-15)
Primary citationKuang, S.,Zheng, J.,Yang, H.,Li, S.,Duan, S.,Shen, Y.,Ji, C.,Gan, J.,Xu, X.W.,Li, J.
Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis.
Proc. Natl. Acad. Sci. U.S.A., 114:10642-10647, 2017
Cited by
PubMed: 28928145
DOI: 10.1073/pnas.1708194114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.64 Å)
Structure validation

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