5WQT
Structure of a protein involved in pyroptosis
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | GLY86 |
| A | MSE87 |
| A | HOH404 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | LEU58 |
| A | MSE146 |
| A | THR178 |
| A | PRO179 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ALA53 |
| A | GLU56 |
| B | GLU5 |
| B | GLY6 |
| A | LEU49 |
| A | ARG52 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue CIT A 304 |
| Chain | Residue |
| A | LEU49 |
| A | ALA50 |
| A | ALA53 |
| A | LEU70 |
| A | ASP71 |
| A | CIT305 |
| A | HOH406 |
| B | GLY6 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CIT A 305 |
| Chain | Residue |
| A | ASP71 |
| A | CIT304 |
| A | HOH406 |
| B | GLU10 |
| B | GLU18 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Region: {"description":"Linker helix loop","evidences":[{"source":"PubMed","id":"28928145","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Cleavage; by papain","evidences":[{"source":"PubMed","id":"35794369","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"32820063","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
