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6N9O

Crystal structure of human GSDMD

Summary for 6N9O
Entry DOI10.2210/pdb6n9o/pdb
DescriptorGasdermin-D (1 entity in total)
Functional Keywordspyroptosis, gasdermin d, inflammasome, autoinhibition, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight211979.84
Authors
Liu, Z.,Wang, C.,Yang, J.,Xiao, T.S. (deposition date: 2018-12-03, release date: 2019-06-05, Last modification date: 2023-10-11)
Primary citationLiu, Z.,Wang, C.,Yang, J.,Zhou, B.,Yang, R.,Ramachandran, R.,Abbott, D.W.,Xiao, T.S.
Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 51:43-, 2019
Cited by
PubMed: 31097341
DOI: 10.1016/j.immuni.2019.04.017
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.5 Å)
Structure validation

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