7QO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qo5 by Molmil](/molmil-images/mine/7qo5) | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-03-16 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
|
|
5L9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l9t by Molmil](/molmil-images/mine/5l9t) | Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. | Deposit date: | 2016-06-11 | Release date: | 2016-10-26 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
|
|
6JMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jma by Molmil](/molmil-images/mine/6jma) | cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome | Descriptor: | DNA I&J, Histone H2A, Histone H2B 1.1, ... | Authors: | Jang, S, Song, J.J. | Deposit date: | 2019-03-07 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
|
|
7QO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qo4 by Molmil](/molmil-images/mine/7qo4) | 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) | Descriptor: | 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
|
|
4WHV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4whv by Molmil](/molmil-images/mine/4whv) | E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B | Descriptor: | E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-09-23 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (8.3 Å) | Cite: | RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
|
|
5A5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a5b by Molmil](/molmil-images/mine/5a5b) | Structure of the 26S proteasome-Ubp6 complex | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. | Deposit date: | 2015-06-17 | Release date: | 2015-07-22 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
6TBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tbm by Molmil](/molmil-images/mine/6tbm) | Structure of SAGA bound to TBP, including Spt8 and DUB | Descriptor: | Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... | Authors: | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | Deposit date: | 2019-11-01 | Release date: | 2020-02-12 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Structure of SAGA and mechanism of TBP deposition on gene promoters. Nature, 577, 2020
|
|
5VEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vey by Molmil](/molmil-images/mine/5vey) | Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708) | Descriptor: | E3 ubiquitin-protein ligase RNF169, Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B | Authors: | Hu, Q, Botuyan, M.V, Cui, G, Mer, G. | Deposit date: | 2017-04-06 | Release date: | 2017-05-17 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18. Mol. Cell, 66, 2017
|
|
5ZD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zd0 by Molmil](/molmil-images/mine/5zd0) | Solution structure of human ubiquitin with three alanine mutations in living eukaryotic cells by in-cell NMR spectroscopy | Descriptor: | ubiquitin | Authors: | Tanaka, T, Ikeya, T, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2018-02-22 | Release date: | 2019-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019
|
|
6QF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qf8 by Molmil](/molmil-images/mine/6qf8) | |
2K25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k25 by Molmil](/molmil-images/mine/2k25) | |
6K4I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k4i by Molmil](/molmil-images/mine/6k4i) | The partially disordered conformation of ubiquitin (Q41N variant) | Descriptor: | ubiquitin | Authors: | Wakamoto, T, Ikeya, T, Kitazawa, S, Baxter, N.J, Williamson, M.P, Kitahara, R. | Deposit date: | 2019-05-24 | Release date: | 2019-10-30 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Paramagnetic relaxation enhancement-assisted structural characterization of a partially disordered conformation of ubiquitin. Protein Sci., 28, 2019
|
|
2LVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lvo by Molmil](/molmil-images/mine/2lvo) | Structure of the gp78CUE domain bound to monubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
|
|
5XBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xbo by Molmil](/molmil-images/mine/5xbo) | Lanthanoid tagging via an unnatural amino acid for protein structure characterization | Descriptor: | Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A | Authors: | Jiang, W, Gu, X, Dong, X, Tang, C. | Deposit date: | 2017-03-21 | Release date: | 2017-05-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Lanthanoid tagging via an unnatural amino acid for protein structure characterization J. Biomol. NMR, 67, 2017
|
|
2JRI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jri by Molmil](/molmil-images/mine/2jri) | Solution structure of the Josephin domain of Ataxin-3 in complex with ubiquitin molecule. | Descriptor: | Ataxin-3, UBC protein | Authors: | Nicastro, G, Masino, L, Esposito, V, Menon, R, Pastore, A. | Deposit date: | 2007-06-27 | Release date: | 2008-07-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Understanding the plasticity of the ubiquitin-protein recognition code: the josephin domain of ataxin-3 is a diubiquitin binding motif To be Published
|
|
2MBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mbo by Molmil](/molmil-images/mine/2mbo) | |
2Z59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z59 by Molmil](/molmil-images/mine/2z59) | Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin | Descriptor: | Protein ADRM1, Ubiquitin | Authors: | Chen, X, Schreiner, P, Groll, M, Walters, K.J. | Deposit date: | 2007-07-01 | Release date: | 2008-05-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature, 453, 2008
|
|
2MBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mbq by Molmil](/molmil-images/mine/2mbq) | |
6KOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kow by Molmil](/molmil-images/mine/6kow) | |
2LZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lz6 by Molmil](/molmil-images/mine/2lz6) | Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications | Descriptor: | CD2-associated protein, Ubiquitin | Authors: | Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N. | Deposit date: | 2012-09-24 | Release date: | 2013-10-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. Plos One, 8, 2013
|
|
1UD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ud7 by Molmil](/molmil-images/mine/1ud7) | SOLUTION STRUCTURE OF THE DESIGNED HYDROPHOBIC CORE MUTANT OF UBIQUITIN, 1D7 | Descriptor: | PROTEIN (UBIQUITIN CORE MUTANT 1D7) | Authors: | Johnson, E.C, Lazar, G.A, Desjarlais, J.R, Handel, T.M. | Deposit date: | 1999-04-07 | Release date: | 1999-05-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin. Structure Fold.Des., 7, 1999
|
|
5XK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xk4 by Molmil](/molmil-images/mine/5xk4) | Retracted state of S65-phosphorylated ubiquitin | Descriptor: | Polyubiquitin-B | Authors: | Dong, X, Gong, Z, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | Deposit date: | 2017-05-05 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5XK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xk5 by Molmil](/molmil-images/mine/5xk5) | Relaxed state of S65-phosphorylated ubiquitin | Descriptor: | Polyubiquitin-B | Authors: | Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | Deposit date: | 2017-05-05 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6KOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kox by Molmil](/molmil-images/mine/6kox) | |
2RR9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rr9 by Molmil](/molmil-images/mine/2rr9) | The solution structure of the K63-Ub2:tUIMs complex | Descriptor: | Putative uncharacterized protein UIMC1, ubiquitin | Authors: | Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M. | Deposit date: | 2010-06-16 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The solution structure of the K63-Ub2:tUIMs complex To be Published
|
|