Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications

Summary for 2LZ6

DescriptorUbiquitin, CD2-associated protein (2 entities in total)
Functional Keywordssignaling protein
Biological sourceHomo sapiens (human)
Cellular locationUbiquitin: Cytoplasm  P0CG48
Cytoplasm, cytoskeleton Q9JLQ0
Total number of polymer chains2
Total molecular weight15723.74
Ortega-Roldan, J.,Azuaga, A.,Blackledge, M.,Van Nuland, N. (deposition date: 2012-09-24, release date: 2013-10-02, Last modification date: 2016-04-27)
Primary citation
Ortega Roldan, J.L.,Casares, S.,Ringkjbing Jensen, M.,Cardenes, N.,Bravo, J.,Blackledge, M.,Azuaga, A.I.,van Nuland, N.A.
Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications.
Plos One, 8:e73018-e73018, 2013
PubMed: 24039852 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0073018
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers62.2%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report