6UE7
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![BU of 6ue7 by Molmil](/molmil-images/mine/6ue7) | Structure of dimeric sIgA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
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6UE9
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![BU of 6ue9 by Molmil](/molmil-images/mine/6ue9) | Structure of tetrameric sIgA complex (Class 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
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6UEA
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![BU of 6uea by Molmil](/molmil-images/mine/6uea) | Structure of pentameric sIgA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
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6UE8
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![BU of 6ue8 by Molmil](/molmil-images/mine/6ue8) | Structure of tetrameric sIgA complex (Class 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
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8SKV
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![BU of 8skv by Molmil](/molmil-images/mine/8skv) | |
6LX3
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![BU of 6lx3 by Molmil](/molmil-images/mine/6lx3) | Cryo-EM structure of human secretory immunoglobulin A | Descriptor: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor | Authors: | Wang, Y, Wang, G, Li, Y, Xiao, J. | Deposit date: | 2020-02-10 | Release date: | 2020-05-27 | Last modified: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin. Cell Res., 30, 2020
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7YSG
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![BU of 7ysg by Molmil](/molmil-images/mine/7ysg) | Cryo-EM structure of human FcmR bound to sIgM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-12 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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8SKU
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![BU of 8sku by Molmil](/molmil-images/mine/8sku) | Structure of human SIgA1 in complex with human CD89 (FcaR1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Liu, Q, Stadtmueller, B.M. | Deposit date: | 2023-04-20 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. Nat Commun, 14, 2023
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6LXW
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![BU of 6lxw by Molmil](/molmil-images/mine/6lxw) | Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA | Descriptor: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ... | Authors: | Wang, Y, Wang, G, Li, Y, Xiao, J. | Deposit date: | 2020-02-12 | Release date: | 2020-05-27 | Last modified: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin. Cell Res., 30, 2020
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7K0C
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![BU of 7k0c by Molmil](/molmil-images/mine/7k0c) | Structure of Secretory IgM Core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, Immunoglobulin heavy constant mu, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2020-09-04 | Release date: | 2021-01-20 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the human secretory immunoglobulin M core. Structure, 29, 2021
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7YG2
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![BU of 7yg2 by Molmil](/molmil-images/mine/7yg2) | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DBLMSP2, ... | Authors: | Shen, H, Ji, C, Xiao, J. | Deposit date: | 2022-07-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M. Nat Commun, 14, 2023
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7YTC
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![BU of 7ytc by Molmil](/molmil-images/mine/7ytc) | Cryo-EM structure of human FcmR bound to IgM-Fc/J | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-14 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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6KXS
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![BU of 6kxs by Molmil](/molmil-images/mine/6kxs) | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Li, Y, Wang, G, Xiao, J. | Deposit date: | 2019-09-12 | Release date: | 2020-02-05 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into immunoglobulin M. Science, 367, 2020
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8BPF
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![BU of 8bpf by Molmil](/molmil-images/mine/8bpf) | FcMR binding at subunit Fcu1 of IgM pentamer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-11-16 | Release date: | 2023-04-12 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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7Y0H
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![BU of 7y0h by Molmil](/molmil-images/mine/7y0h) | |
8GZN
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![BU of 8gzn by Molmil](/molmil-images/mine/8gzn) | IgM-var2CSA complex | Descriptor: | Erythrocyte membrane protein 1, Immunoglobulin J chain, Immunoglobulin heavy constant mu | Authors: | Akhouri, R.R, Goel, S, Skoglund, U. | Deposit date: | 2022-09-27 | Release date: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A. Nat Commun, 14, 2023
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7Y0J
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![BU of 7y0j by Molmil](/molmil-images/mine/7y0j) | |
8BPE
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![BU of 8bpe by Molmil](/molmil-images/mine/8bpe) | 8:1 binding of FcMR on IgM pentameric core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-11-16 | Release date: | 2023-04-12 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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7YTD
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![BU of 7ytd by Molmil](/molmil-images/mine/7ytd) | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-14 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7Y09
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![BU of 7y09 by Molmil](/molmil-images/mine/7y09) | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Shen, H, Ji, C, Xiao, J. | Deposit date: | 2022-06-03 | Release date: | 2023-03-29 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M. Nat Commun, 14, 2023
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8ADY
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![BU of 8ady by Molmil](/molmil-images/mine/8ady) | Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8ADZ
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![BU of 8adz by Molmil](/molmil-images/mine/8adz) | Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8AE3
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![BU of 8ae3 by Molmil](/molmil-images/mine/8ae3) | Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8AE0
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![BU of 8ae0 by Molmil](/molmil-images/mine/8ae0) | Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8AE2
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![BU of 8ae2 by Molmil](/molmil-images/mine/8ae2) | Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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