8SKV

Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)

Summary for 8SKV

• Entry DOI: 10.2210/pdb8skv/pdb
• EMDB information: 40568
• Descriptor: Immunoglobulin heavy constant alpha 1, Secretory component, Immunoglobulin J chain, ... (6 entities in total)
• Functional Keywords: secretory immunoglobulin a, siga, iga, group a streptococcus, streptococcus pyogenes m protein, m4, arp4, infectious disease, protein complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 305408.38

Authors

Liu, Q.,Stadtmueller, B.M. (deposition date: 2023-04-20, release date: 2023-10-25, Last modification date: 2023-11-08)

• Primary citation: Liu, Q.,Stadtmueller, B.M.; SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.; Nat Commun, 14:6726-6726, 2023; PubMed: 37872175; DOI: 10.1038/s41467-023-42469-y

Experimental method

ELECTRON MICROSCOPY (3.1 Å)