8SKV
Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Immunoglobulin heavy constant alpha 1 | polymer | 353 | 37687.5 | 4 | UniProt (P01876) Pfam (PF07654) Pfam (PF00047) In PDB | Homo sapiens (human) | Ig alpha-1 chain C region,Ig alpha-1 chain C region BUR,Ig alpha-1 chain C region TRO |
2 | E | Secretory component | polymer | 553 | 61095.6 | 1 | UniProt (P01833) Pfam (PF07686) In PDB | Homo sapiens (human) | Polymeric immunoglobulin receptor |
3 | J | Immunoglobulin J chain | polymer | 137 | 15611.5 | 1 | UniProt (P01591) Pfam (PF15097) In PDB | Homo sapiens (human) | Joining chain of multimeric IgA and IgM |
4 | a, b | IgA receptor | polymer | 321 | 37352.7 | 2 | UniProt (P13050) Pfam (PF02370) In PDB | Streptococcus pyogenes serotype M4 | |
5 | G, H, I, O | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
6 | A, B, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
E: 1 - 547 (UniProt: P01833)
a, b: 1 - 315 (UniProt: P13050)
PDB | External Database | Details |
---|---|---|
His 548 | - | expression tag |
His 549 | - | expression tag |
His 550 | - | expression tag |
His 551 | - | expression tag |
His 552 | - | expression tag |
His 553 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 316 | - | expression tag |
His 317 | - | expression tag |
His 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 302162.3 | |
Branched | Number of molecules | 4 |
Total formula weight | 1697.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1548.5 | |
All* | Total formula weight | 305408.4 |