7Y0H

Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum VAR2CSA FCR3

Summary for 7Y0H

• Entry DOI: 10.2210/pdb7y0h/pdb
• EMDB information: 33542
• Descriptor: Immunoglobulin heavy constant mu, Immunoglobulin J chain, Erythrocyte membrane protein 1, ... (5 entities in total)
• Functional Keywords: complex, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 743248.88

Authors

Ji, C.,Xiao, J. (deposition date: 2022-06-05, release date: 2023-04-12, Last modification date: 2023-10-11)

• Primary citation: Ji, C.,Shen, H.,Su, C.,Li, Y.,Chen, S.,Sharp, T.H.,Xiao, J.; Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M; Nat Commun, 14:2650-, 2023; DOI: 10.1038/s41467-023-38320-z

Experimental method

ELECTRON MICROSCOPY (3.56 Å)