7YG2

Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2

Summary for 7YG2

• Entry DOI: 10.2210/pdb7yg2/pdb
• EMDB information: 33805
• Descriptor: DBLMSP2, Immunoglobulin heavy constant mu, Immunoglobulin J chain, ... (5 entities in total)
• Functional Keywords: malaria, immunoglobin, immune system
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 12
• Total formula weight: 473183.46

Authors

Shen, H.,Ji, C.,Xiao, J. (deposition date: 2022-07-09, release date: 2023-03-29, Last modification date: 2023-10-11)

• Primary citation: Ji, C.,Shen, H.,Su, C.,Li, Y.,Chen, S.,Sharp, T.H.,Xiao, J.; Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M; Nat Commun, 14:2650-, 2023; DOI: 10.1038/s41467-023-38320-z

Experimental method

ELECTRON MICROSCOPY (3.32 Å)