8AE0

Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3

Summary for 8AE0

• Entry DOI: 10.2210/pdb8ae0/pdb
• EMDB information: 15377
• Descriptor: IgM Fab, light chain, IgM Fab, heavy chain, IgM C2-domain from mouse, ... (7 entities in total)
• Functional Keywords: full-length human immunoglobulin m, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 17
• Total formula weight: 559150.73

Authors

Chen, Q.,Rosenthal, P.,Tolar, P. (deposition date: 2022-07-12, release date: 2022-10-26, Last modification date: 2022-11-09)

• Primary citation: Chen, Q.,Menon, R.,Calder, L.J.,Tolar, P.,Rosenthal, P.B.; Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.; Nat Commun, 13:6314-6314, 2022; PubMed: 36274064; DOI: 10.1038/s41467-022-34090-2

Experimental method

ELECTRON MICROSCOPY (7.1 Å)