7Y0J

Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum TM284VAR1

Summary for 7Y0J

Entry DOI	10.2210/pdb7y0j/pdb
EMDB information	33547
Descriptor	Erythrocyte membrane protein 2 variant TM284var1, Immunoglobulin heavy constant mu, Immunoglobulin J chain, ... (5 entities in total)
Functional Keywords	complex, antibody, immune system
Biological source	Plasmodium falciparum (malaria parasite P. falciparum) More
Total number of polymer chains	12
Total formula weight	714382.69
Authors	Ji, C.,Xiao, J. (deposition date: 2022-06-05, release date: 2023-04-05, Last modification date: 2023-10-11)
Primary citation	Ji, C.,Shen, H.,Su, C.,Li, Y.,Chen, S.,Sharp, T.H.,Xiao, J. Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M Nat Commun, 14:2650-, 2023 Cited by DOI: 10.1038/s41467-023-38320-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.62 Å)

Structure validation