1BTE
| CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE TYPE II ACTIVIN RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (ACTIVIN RECEPTOR TYPE II) | Authors: | Greenwald, J, Fischer, W, Vale, W, Choe, S. | Deposit date: | 1998-09-01 | Release date: | 1999-02-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase. Nat.Struct.Biol., 6, 1999
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1ES7
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1LX5
| Crystal Structure of the BMP7/ActRII Extracellular Domain Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin Type II Receptor, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Greenwald, J, Groppe, J, Kwiatkowski, W, Choe, S. | Deposit date: | 2002-06-04 | Release date: | 2003-04-01 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The BMP7/ActRII Extracellular Domain Complex Provides New Insights into
the Cooperative Nature of Receptor Assembly Mol.Cell, 11, 2003
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1NYU
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1NYS
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1REW
| Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor | Descriptor: | bone morphogenetic protein 2, bone morphogenetic protein receptor type IA | Authors: | Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D. | Deposit date: | 2003-11-07 | Release date: | 2004-05-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.863 Å) | Cite: | Molecular recognition of BMP-2 and BMP receptor IA. Nat.Struct.Mol.Biol., 11, 2004
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1S4Y
| Crystal structure of the activin/actrIIb extracellular domain | Descriptor: | Activin receptor type IIB precursor, Inhibin beta A chain | Authors: | Greenwald, J, Vega, M.E, Allendorph, G.P, Fischer, W.H, Vale, W, Choe, S, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2004-01-19 | Release date: | 2004-08-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-beta Family Receptors. Mol.Cell, 15, 2004
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2GOO
| Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Activin receptor type 2A, Bone morphogenetic protein 2, ... | Authors: | Allendorph, G.P, Choe, S. | Deposit date: | 2006-04-13 | Release date: | 2006-05-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HLR
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2HLQ
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2H64
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2H62
| Crystal structure of a ternary ligand-receptor complex of BMP-2 | Descriptor: | Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Mueller, T.D. | Deposit date: | 2006-05-30 | Release date: | 2007-04-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. Bmc Struct.Biol., 7, 2007
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2QJ9
| Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1 | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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2QJA
| Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12 | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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2QJB
| Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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2PJY
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2K3G
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3EVS
| Crystal structure of the GDF-5:BMP receptor IB complex. | Descriptor: | Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5 | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2008-10-13 | Release date: | 2009-03-10 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity. Embo J., 28, 2009
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3KFD
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3NH7
| Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA | Descriptor: | Antibody fragment Fab AbD1556, heavy chain, light chain, ... | Authors: | Mueller, T.D, Harth, S, Sebald, W. | Deposit date: | 2010-06-14 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity Plos One, 5, 2010
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2L5S
| Solution structure of the extracellular domain of the TGF-beta type I receptor | Descriptor: | TGF-beta receptor type-1 | Authors: | Zuniga, J.E, Ilangovan, U, Pardeep, M, Hinck, C, Huang, T. | Deposit date: | 2010-11-04 | Release date: | 2011-10-26 | Method: | SOLUTION NMR | Cite: | The TbetaR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding J.Mol.Biol., 412, 2011
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3QB4
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4FAO
| Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ... | Authors: | Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V. | Deposit date: | 2012-05-22 | Release date: | 2012-06-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.357 Å) | Cite: | Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex. J.Biol.Chem., 287, 2012
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5NHR
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5NGV
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