2L5S

Solution structure of the extracellular domain of the TGF-beta type I receptor

Summary for 2L5S

• Entry DOI: 10.2210/pdb2l5s/pdb
• Descriptor: TGF-beta receptor type-1 (1 entity in total)
• Functional Keywords: alk5, transforming growth factor beta, type i receptor, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: P36897
• Total number of polymer chains: 1
• Total formula weight: 9472.83

Authors

Zuniga, J.E.,Ilangovan, U.,Pardeep, M.,Hinck, C.,Huang, T. (deposition date: 2010-11-04, release date: 2011-10-26)

• Primary citation: Zuniga, J.E.,Ilangovan, U.,Mahlawat, P.,Hinck, C.S.,Huang, T.,Groppe, J.C.,McEwen, D.G.,Hinck, A.P.; The TbetaR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding; J.Mol.Biol., 412:601-618, 2011; PubMed: 21821041; DOI: 10.1016/j.jmb.2011.07.046

Experimental method

SOLUTION NMR