4GCA
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![BU of 4gca by Molmil](/molmil-images/mine/4gca) | Complex of Aldose Reductase with inhibitor IDD 1219 | Descriptor: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2,6-dimethyl-5-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]pyridin-3-yl}acetic acid | Authors: | Podjarny, A.D, Van Zandt, M, Geraci, L.S. | Deposit date: | 2012-07-30 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Complex of Aldose Reductase with inhibitor IDD 1219 TO BE PUBLISHED
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4GCZ
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![BU of 4gcz by Molmil](/molmil-images/mine/4gcz) | Structure of a blue-light photoreceptor | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Blue-light photoreceptor, Sensor protein fixL, ... | Authors: | Diensthuber, R.P, Bommer, M, Moglich, A. | Deposit date: | 2012-07-31 | Release date: | 2013-06-19 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Full-length structure of a sensor histidine kinase pinpoints coaxial coiled coils as signal transducers and modulators. Structure, 21, 2013
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3N3B
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![BU of 3n3b by Molmil](/molmil-images/mine/3n3b) | Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI with a Trapped Peroxide | Descriptor: | FLAVIN MONONUCLEOTIDE, HYDROGEN PEROXIDE, MANGANESE (II) ION, ... | Authors: | Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. | Deposit date: | 2010-05-19 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010
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4GGC
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![BU of 4ggc by Molmil](/molmil-images/mine/4ggc) | |
3NM1
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![BU of 3nm1 by Molmil](/molmil-images/mine/3nm1) | The Crystal Structure of Candida glabrata THI6, a Bifunctional Enzyme involved in Thiamin Biosyhthesis of Eukaryotes | Descriptor: | 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, MAGNESIUM ION, ... | Authors: | Paul, D, Chatterjee, A, Begley, T.P, Ealick, S.E. | Deposit date: | 2010-06-21 | Release date: | 2010-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.211 Å) | Cite: | Domain Organization in Candida glabrata THI6, a Bifunctional Enzyme Required for Thiamin Biosynthesis in Eukaryotes . Biochemistry, 49, 2010
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3N4D
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![BU of 3n4d by Molmil](/molmil-images/mine/3n4d) | |
4GPE
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![BU of 4gpe by Molmil](/molmil-images/mine/4gpe) | Crystal Structure of Benzoylformate Decarboxylase Mutant L403M | Descriptor: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... | Authors: | Novak, W.R.P, Andrews, F.H, Tom, A.R, Gunderman, P.R, McLeish, M.J. | Deposit date: | 2012-08-20 | Release date: | 2013-05-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | A bulky hydrophobic residue is not required to maintain the v-conformation of enzyme-bound thiamin diphosphate. Biochemistry, 52, 2013
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4HC7
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![BU of 4hc7 by Molmil](/molmil-images/mine/4hc7) | Crystal structure of the full DNA binding domain of GATA3-complex 2 | Descriptor: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | Authors: | Chen, Y, Bates, D.L, Dey, R, Chen, L. | Deposit date: | 2012-09-28 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
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4HDM
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![BU of 4hdm by Molmil](/molmil-images/mine/4hdm) | Crystal Structure of ArsAB in Complex with p-cresol | Descriptor: | 1,2-ETHANEDIOL, ArsA, ArsB, ... | Authors: | Newmister, S.A, Chan, C.H, Escalante-Semerena, J.C, Rayment, I. | Deposit date: | 2012-10-02 | Release date: | 2012-10-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry, 51, 2012
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4GQI
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![BU of 4gqi by Molmil](/molmil-images/mine/4gqi) | Synthesis of novel MT3 receptor ligands via unusual Knoevenagel condensation | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, N-{(3R)-3-[2-(acetylamino)ethyl]-2-oxo-2,3-dihydro-1H-indol-5-yl}acetamide, ... | Authors: | Volkova, M.S, Jensen, K.C, Lozinskaya, N.A, Sosonyuk, S.E, Proskurnina, M.V, Mesecar, A.D, Zefirov, N.S. | Deposit date: | 2012-08-23 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Synthesis of novel МТ3 receptor ligands via an unusual Knoevenagel condensation. Bioorg.Med.Chem.Lett., 22, 2012
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4GQT
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![BU of 4gqt by Molmil](/molmil-images/mine/4gqt) | N-terminal domain of C. elegans Hsp90 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Heat shock protein 90, ZINC ION | Authors: | Osipiuk, J, Chhor, G, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-08-23 | Release date: | 2012-09-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | N-terminal domain of C. elegans Hsp90 To be Published
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4HG2
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![BU of 4hg2 by Molmil](/molmil-images/mine/4hg2) | The Structure of a Putative Type II Methyltransferase from Anaeromyxobacter dehalogenans. | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Methyltransferase type 11 | Authors: | Cuff, M.E, Chhor, G, Clancy, S, Brown, R.N, Cort, J.R, Heffron, F, Nakayasu, E.S, Adkins, J.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) | Deposit date: | 2012-10-05 | Release date: | 2012-10-17 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Structure of a Putative Type II Methyltransferase from Anaeromyxobacter dehalogenans. TO BE PUBLISHED
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3NFS
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![BU of 3nfs by Molmil](/molmil-images/mine/3nfs) | Crystal structure the Fab fragment of therapeutic antibody daclizumab | Descriptor: | Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | Deposit date: | 2010-06-10 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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3N3A
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![BU of 3n3a by Molmil](/molmil-images/mine/3n3a) | Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI | Descriptor: | FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ... | Authors: | Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. | Deposit date: | 2010-05-19 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010
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4GU7
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![BU of 4gu7 by Molmil](/molmil-images/mine/4gu7) | Crystal structure of DyP-type peroxidase (SCO7193) from Streptomyces coelicolor | Descriptor: | NICKEL (II) ION, PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein SCO7193 | Authors: | Lukk, T, Hetta, A.M.A, Jones, A, Solbiati, J, Majumdar, S, Cronan, J.E, Gerlt, J.A, Nair, S.K. | Deposit date: | 2012-08-29 | Release date: | 2013-09-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | DyP-type peroxidases from Stretptomyces and Thermobifida can modify organosolv lignin. To be Published
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4GUL
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![BU of 4gul by Molmil](/molmil-images/mine/4gul) | Study on structure and function relationships in human ferric Pirin | Descriptor: | FE (III) ION, Pirin | Authors: | Liu, F, Rehmani, I, Fu, R, Esaka, S, Chen, L, Serrano, V, Liu, A. | Deposit date: | 2012-08-29 | Release date: | 2013-05-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110, 2013
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4GWV
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![BU of 4gwv by Molmil](/molmil-images/mine/4gwv) | Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate | Descriptor: | CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. | Deposit date: | 2012-09-03 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallogr.,Sect.D, 69, 2013
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4GXP
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![BU of 4gxp by Molmil](/molmil-images/mine/4gxp) | Chimeric Family 1 beta-glucosidase made with non-contiguous SCHEMA | Descriptor: | Beta-glucosidase Chimeric protein | Authors: | Smith, M.A, Romero, P.A, Wu, T, Brustad, E.M, Arnold, F.H. | Deposit date: | 2012-09-04 | Release date: | 2013-01-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Chimeragenesis of distantly-related proteins by noncontiguous recombination. Protein Sci., 22, 2013
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3N39
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![BU of 3n39 by Molmil](/molmil-images/mine/3n39) | Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with NrdI | Descriptor: | FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ... | Authors: | Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. | Deposit date: | 2010-05-19 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010
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3N96
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4GZU
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![BU of 4gzu by Molmil](/molmil-images/mine/4gzu) | Crystal structure of the DH-PH-PH domain of FARP2 | Descriptor: | FERM, RhoGEF and pleckstrin domain-containing protein 2 | Authors: | He, X, Zhang, X. | Deposit date: | 2012-09-06 | Release date: | 2013-03-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2. Structure, 21, 2013
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3N7C
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![BU of 3n7c by Molmil](/molmil-images/mine/3n7c) | Crystal structure of the RAN binding domain from the nuclear pore complex component NUP2 from Ashbya gossypii | Descriptor: | ABR034Wp | Authors: | Sampathkumar, P, Manglicmot, D, Gilmore, J, Bain, K, Gheyi, T, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-26 | Release date: | 2010-06-16 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structure of the RAN binding domain from the nuclear pore complex component NUP2 from Ashbya gossypii To be Published
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4H6W
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4H2U
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![BU of 4h2u by Molmil](/molmil-images/mine/4h2u) | Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with cognate carrier protein and ATP | Descriptor: | 4'-PHOSPHOPANTETHEINE, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M. | Deposit date: | 2012-09-13 | Release date: | 2013-03-06 | Last modified: | 2013-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation. Structure, 21, 2013
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4HBA
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![BU of 4hba by Molmil](/molmil-images/mine/4hba) | Structural and Catalytic Characterization of a Thermal and Acid Stable Variant of Human Carbonic Anhydrase II Containing an Engineered Disulfide Bond | Descriptor: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | Authors: | Boone, C.D, Habibzadegan, A, McKenna, R. | Deposit date: | 2012-09-27 | Release date: | 2013-07-31 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.762 Å) | Cite: | Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond. Acta Crystallogr.,Sect.D, 69, 2013
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