4K7D

Crystal Structure of Parkin C-terminal RING domains

Summary for 4K7D

Entry DOI	10.2210/pdb4k7d/pdb
Descriptor	E3 ubiquitin-protein ligase parkin, ZINC ION, MALONATE ION, ... (5 entities in total)
Functional Keywords	ring domains, zinc fingers, rbr ubiquitin ligase, e3 ubiquitin protein ligase, ubiquitin, ubch7, ligase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Nucleus (By similarity): Q9JK66
Total number of polymer chains	3
Total formula weight	112404.62
Authors	Sauve, V.,Trempe, J.-F.,Menade, M.,Gehring, K. (deposition date: 2013-04-17, release date: 2013-05-15, Last modification date: 2024-02-28)
Primary citation	Trempe, J.F.,Sauve, V.,Grenier, K.,Seirafi, M.,Tang, M.Y.,Menade, M.,Al-Abdul-Wahid, S.,Krett, J.,Wong, K.,Kozlov, G.,Nagar, B.,Fon, E.A.,Gehring, K. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340:1451-1455, 2013 Cited by PubMed: 23661642 DOI: 10.1126/science.1237908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation