4TWA

Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum

Summary for 4TWA

Entry DOI	10.2210/pdb4twa/pdb
Descriptor	Proline--tRNA ligase, CHLORIDE ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	protein translation, halofuginone, malaria, inhibitor, prs, synthetase, ligase
Biological source	Plasmodium falciparum
Cellular location	Cytoplasm : Q8I5R7
Total number of polymer chains	2
Total formula weight	116871.79
Authors	Jain, V.,Yogavel, M.,Sharma, A. (deposition date: 2014-06-30, release date: 2014-08-13, Last modification date: 2023-09-27)
Primary citation	Jain, V.,Kikuchi, H.,Oshima, Y.,Sharma, A.,Yogavel, M. Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase. J. Struct. Funct. Genomics, 15:181-190, 2014 Cited by PubMed: 25047712 DOI: 10.1007/s10969-014-9186-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation