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6BCU
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BU of 6bcu by Molmil
Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ...
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
6BK8
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BU of 6bk8 by Molmil
S. cerevisiae spliceosomal post-catalytic P complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ...
Authors:Liu, S, Li, X, Zhou, Z.H, Zhao, R.
Deposit date:2017-11-07
Release date:2018-02-21
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the yeast spliceosomal postcatalytic P complex.
Science, 358, 2017
6G53
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BU of 6g53 by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State E
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2018-03-28
Release date:2018-06-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6G18
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BU of 6g18 by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State C
Descriptor: 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ...
Authors:Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2018-03-20
Release date:2018-06-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6G5H
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BU of 6g5h by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2018-03-29
Release date:2018-06-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6G51
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BU of 6g51 by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State D
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2018-03-28
Release date:2018-06-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6GDG
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BU of 6gdg by Molmil
Cryo-EM structure of the adenosine A2A receptor bound to a miniGs heterotrimer
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Garcia-Nafria, J, Lee, Y.
Deposit date:2018-04-23
Release date:2018-05-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein.
Elife, 7, 2018
6GSN
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BU of 6gsn by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GQV
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BU of 6gqv by Molmil
Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-08
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6GZ3
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BU of 6gz3 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6HCJ
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BU of 6hcj by Molmil
Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCQ
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BU of 6hcq by Molmil
Structure of the rabbit collided di-ribosome (collided monosome)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-16
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCM
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BU of 6hcm by Molmil
Structure of the rabbit collided di-ribosome (stalled monosome)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6GQB
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BU of 6gqb by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6HHQ
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BU of 6hhq by Molmil
Crystal structure of compound C45 bound to the yeast 80S ribosome
Descriptor: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ...
Authors:Pellegrino, S, Vanderwal, C.D, Yusupov, M.
Deposit date:2018-08-28
Release date:2019-02-20
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.10000038 Å)
Cite:Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6HCF
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BU of 6hcf by Molmil
Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6G79
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BU of 6g79 by Molmil
Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor
Descriptor: 2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium, 5-hydroxytryptamine receptor 1B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Garcia-Nafria, J, Nehme, R, Edwards, P, Tate, C.G.
Deposit date:2018-04-05
Release date:2018-06-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go.
Nature, 558, 2018
6FT6
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BU of 6ft6 by Molmil
Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors
Descriptor: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ...
Authors:Schuller, J.M, Falk, S, Conti, E.
Deposit date:2018-02-20
Release date:2018-03-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
6FYX
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BU of 6fyx by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6ID0
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BU of 6id0 by Molmil
Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Zhan, X, Yan, C, Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ICZ
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BU of 6icz by Molmil
Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Zhang, X, Zhan, X, Yan, C, Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6GQ1
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BU of 6gq1 by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019

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數據於2024-06-26公開中

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