5UQ0
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1LGP
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![BU of 1lgp by Molmil](/molmil-images/mine/1lgp) | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein complexed with tungstate | Descriptor: | TUNGSTATE(VI)ION, cell cycle checkpoint protein CHFR | Authors: | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | Deposit date: | 2002-04-16 | Release date: | 2002-05-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate. Structure, 10, 2002
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3IUY
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![BU of 3iuy by Molmil](/molmil-images/mine/3iuy) | Crystal structure of DDX53 DEAD-box domain | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX53 | Authors: | Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-31 | Release date: | 2009-10-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
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5O1Y
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![BU of 5o1y by Molmil](/molmil-images/mine/5o1y) | Structure of Nrd1 RNA binding domain in complex with RNA (GUAA) | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Protein NRD1, ... | Authors: | Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B. | Deposit date: | 2017-05-19 | Release date: | 2017-08-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition. Nucleic Acids Res., 45, 2017
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1LEW
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![BU of 1lew by Molmil](/molmil-images/mine/1lew) | CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A | Descriptor: | Mitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A | Authors: | Chang, C.-I, Xu, B.-E, Akella, R, Cobb, M.H, Goldsmith, E.J. | Deposit date: | 2002-04-10 | Release date: | 2002-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. Mol.Cell, 9, 2002
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5O3W
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![BU of 5o3w by Molmil](/molmil-images/mine/5o3w) | Structural characterization of the fast and promiscuous macrocyclase from plant - PCY1-S562A bound to Presegetalin A1 | Descriptor: | MAGNESIUM ION, Peptide cyclase 1, Presegetalin A1, ... | Authors: | Ludewig, H, Czekster, C.M, Bent, A.F, Naismith, J.H. | Deposit date: | 2017-05-25 | Release date: | 2018-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates. ACS Chem. Biol., 13, 2018
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1LGQ
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![BU of 1lgq by Molmil](/molmil-images/mine/1lgq) | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein | Descriptor: | cell cycle checkpoint protein CHFR | Authors: | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | Deposit date: | 2002-04-16 | Release date: | 2002-05-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate. Structure, 10, 2002
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1L8Z
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![BU of 1l8z by Molmil](/molmil-images/mine/1l8z) | Solution structure of HMG box 5 in human upstream binding factor | Descriptor: | upstream binding factor 1 | Authors: | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | Deposit date: | 2002-03-22 | Release date: | 2002-06-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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1L2J
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![BU of 1l2j by Molmil](/molmil-images/mine/1l2j) | Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol | Descriptor: | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, ESTROGEN RECEPTOR BETA | Authors: | Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L. | Deposit date: | 2002-02-21 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat.Struct.Biol., 9, 2002
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5T46
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![BU of 5t46 by Molmil](/molmil-images/mine/5t46) | Crystal structure of the human eIF4E-eIF4G complex | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ... | Authors: | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | Deposit date: | 2016-08-29 | Release date: | 2016-10-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
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5SZH
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![BU of 5szh by Molmil](/molmil-images/mine/5szh) | Structure of human Rab1b in complex with the bMERB domain of Mical-cL | Descriptor: | MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Goody, R.S, Mueller, M.P, Gazdag, E.M. | Deposit date: | 2016-08-14 | Release date: | 2016-08-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. Elife, 5, 2016
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5O1Z
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5O52
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![BU of 5o52 by Molmil](/molmil-images/mine/5o52) | Glycogen Phosphorylase b in complex with 33b | Descriptor: | (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... | Authors: | Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. | Deposit date: | 2017-05-31 | Release date: | 2017-09-27 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
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2XOC
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![BU of 2xoc by Molmil](/molmil-images/mine/2xoc) | C-terminal cysteine-rich domain of human CHFR bound to mADPr | Descriptor: | ADENINE, ADENOSINE-5'-DIPHOSPHATE, E3 UBIQUITIN-PROTEIN LIGASE CHFR, ... | Authors: | Oberoi, J, Bayliss, R. | Deposit date: | 2010-08-11 | Release date: | 2010-09-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr). J.Biol.Chem., 285, 2010
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5UEC
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![BU of 5uec by Molmil](/molmil-images/mine/5uec) | Crystal Structure of CYP2B6 (Y226H/K262R) in complex with myrtenyl bromide. | Descriptor: | (1S,5R)-2-(bromomethyl)-6,6-dimethylbicyclo[3.1.1]hept-2-ene, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | Authors: | Shah, M.B, Halpert, J.R. | Deposit date: | 2016-12-30 | Release date: | 2017-04-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12, 2017
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5O50
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![BU of 5o50 by Molmil](/molmil-images/mine/5o50) | Glycogen Phosphorylase b in complex with 33a | Descriptor: | (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... | Authors: | Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. | Deposit date: | 2017-05-31 | Release date: | 2017-09-27 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
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3HW2
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![BU of 3hw2 by Molmil](/molmil-images/mine/3hw2) | Crystal structure of the SifA-SKIP(PH) complex | Descriptor: | Pleckstrin homology domain-containing family M member 2, Protein sifA | Authors: | Diacovich, L, Dumont, A, Lafitte, D, Soprano, E, Guilhon, A.-A, Bignon, C, Gorvel, J.-P, Bourne, Y, Meresse, S. | Deposit date: | 2009-06-17 | Release date: | 2009-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis J.Biol.Chem., 284, 2009
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5UAP
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![BU of 5uap by Molmil](/molmil-images/mine/5uap) | Crystal Structure of CYP2B6 (Y226H/K262R) in complex with Bornyl Bromide | Descriptor: | (1R,2R,4R)-2-bromo-1,7,7-trimethylbicyclo[2.2.1]heptane, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | Authors: | Shah, M.B, Halpert, J.R. | Deposit date: | 2016-12-19 | Release date: | 2017-04-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12, 2017
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3HZJ
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![BU of 3hzj by Molmil](/molmil-images/mine/3hzj) | Crystal structure of the RabGAP domain of the RABGAP1L protein | Descriptor: | RAB GTPase-activating protein 1-like, UNKNOWN ATOM OR ION | Authors: | Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-06-23 | Release date: | 2009-07-14 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the RabGAP domain of the RABGAP1L protein To be Published
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5UC4
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![BU of 5uc4 by Molmil](/molmil-images/mine/5uc4) | Hsp90b N-terminal domain with inhibitors | Descriptor: | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Deng, J, Peng, S, Balch, M, Matts, R. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Nat Commun, 9, 2018
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2W6X
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![BU of 2w6x by Molmil](/molmil-images/mine/2w6x) | Crystal structure of Sperm Whale Myoglobin mutant YQRF in complex with Xenon | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | Authors: | Miele, A.E, Draghi, F, Renzi, F, Sciara, G, Johnson, K.A, Vallone, B, Brunori, M, Savino, C. | Deposit date: | 2008-12-19 | Release date: | 2009-12-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | When the Same Fold Does not Mean the Same Function: The Case of Xenon Cavities in Hemoglobin and Myoglobin To be Published
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3HMN
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![BU of 3hmn by Molmil](/molmil-images/mine/3hmn) | Crystal structure of human Mps1 catalytic domain in complex with ATP | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity protein kinase TTK | Authors: | Chu, M.L.H, Chavas, L.M.G, Williams, D.H, Tabernero, L, Eyers, P.A. | Deposit date: | 2009-05-29 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. Biochemistry, 49, 2010
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3HPJ
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1JUF
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![BU of 1juf by Molmil](/molmil-images/mine/1juf) | Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db | Descriptor: | Beta-2-microglobulin, H13b peptide, H2-Db major histocompatibility antigen | Authors: | Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D.C, Nathenson, S.G. | Deposit date: | 2001-08-24 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. J.Immunol., 168, 2002
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5O1T
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![BU of 5o1t by Molmil](/molmil-images/mine/5o1t) | |