1LEW

CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A

Summary for 1LEW

Related1LEZ
DescriptorMitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A (3 entities in total)
Functional Keywordsprotein-peptide complex, transferase, map kinase, serine/threonine-protein kinase, p38, mef2a
Biological sourceMus musculus (Mouse)
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Cellular locationCytoplasm  P47811
Nucleus  Q02078
Total number of polymer chains2
Total molecular weight42717.83
Authors
Chang, C.-I.,Xu, B.-E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2002-04-10, release date: 2002-07-10, Last modification date: 2017-06-21)
Primary citation
Chang, C.I.,Xu, B.E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J.
Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.
Mol.Cell, 9:1241-1249, 2002
PubMed: 12086621 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(02)00525-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers19 0.6% 5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25