5UEC
Crystal Structure of CYP2B6 (Y226H/K262R) in complex with myrtenyl bromide.
Summary for 5UEC
| Entry DOI | 10.2210/pdb5uec/pdb |
| Related | 5UDA |
| Descriptor | Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (5 entities in total) |
| Functional Keywords | oxidoreductase, cytochrome p450 2b6 |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 56961.34 |
| Authors | Shah, M.B.,Halpert, J.R. (deposition date: 2016-12-30, release date: 2017-04-12, Last modification date: 2023-10-04) |
| Primary citation | Shah, M.B.,Liu, J.,Zhang, Q.,Stout, C.D.,Halpert, J.R. Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12:1204-1210, 2017 Cited by PubMed: 28368100DOI: 10.1021/acschembio.7b00056 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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