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3CHN
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BU of 3chn by Molmil
Solution structure of human secretory IgA1
Descriptor: Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component
Authors:Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
Deposit date:2008-03-10
Release date:2008-12-30
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
6AOR
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BU of 6aor by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOT
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BU of 6aot by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 6'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
2RHP
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BU of 2rhp by Molmil
The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Carlson, C.B, Keck, J.L, Mosher, D.F.
Deposit date:2007-10-09
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability.
J.Biol.Chem., 283, 2008
7AQG
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BU of 7aqg by Molmil
Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F)
Descriptor: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1, VHH-2g-42 (Nb42), ...
Authors:Sillen, M, Strelkov, S.V, Declerck, P.J.
Deposit date:2020-10-21
Release date:2021-02-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
Int J Mol Sci, 22, 2021
5MP3
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BU of 5mp3 by Molmil
Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
Descriptor: ENSMUSG00000076577 protein, Igh protein, Microtubule-associated protein
Authors:Skrabana, R, Novak, M, Cehlar, O, Kontsekova, E.
Deposit date:2016-12-15
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
To be published
7Q15
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BU of 7q15 by Molmil
Crystal structure of FcRn and beta-2-microglobulin in complex with IgG1-Fc-MST-HN (efgartigimod)
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, IgG1-Fc-MST-HN, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2021-10-18
Release date:2022-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Nat Commun, 13, 2022
7AJ6
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BU of 7aj6 by Molmil
LN02 Fab
Descriptor: LN02, LN02 heavy chain
Authors:Caillat, C, Fenwick, G, Pantaleo, G, Weissenhorn, W.
Deposit date:2020-09-28
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:LN02 Fab
To Be Published
3CSB
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BU of 3csb by Molmil
Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
Authors:Gilbreth, R.N, Koide, S.
Deposit date:2008-04-09
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
2SPZ
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BU of 2spz by Molmil
STAPHYLOCOCCAL PROTEIN A, Z-DOMAIN, NMR, 10 STRUCTURES
Descriptor: IMMUNOGLOBULIN G BINDING PROTEIN A
Authors:Montelione, G.T, Tashiro, M, Tejero, R, Lyons, B.A.
Deposit date:1998-07-29
Release date:1998-08-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High-resolution solution NMR structure of the Z domain of staphylococcal protein A.
J.Mol.Biol., 272, 1997
7QIV
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BU of 7qiv by Molmil
Structure of human C3b in complex with the EWE nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ...
Authors:Pedersen, H, Andersen, G.R.
Deposit date:2021-12-16
Release date:2022-02-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity.
Front Immunol, 13, 2022
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7C02
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BU of 7c02 by Molmil
Crystal structure of dimeric MERS-CoV receptor binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Dai, L, Qi, J, Gao, G.F.
Deposit date:2020-04-30
Release date:2020-07-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS.
Cell, 182, 2020
8U1R
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BU of 8u1r by Molmil
Prefusion-stabilized Langya virus F protein, variant G99C/I109C
Descriptor: Fusion glycoprotein F
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2023-09-01
Release date:2023-12-27
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
Descriptor: ANT05 H12 fab fragment, heavy chain, light chain, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGI
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BU of 7pgi by Molmil
NaVAb1p (bicelles)
Descriptor: ACETATE ION, Ion transport protein, MAGNESIUM ION, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-14
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.638 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGH
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BU of 7pgh by Molmil
NaVAe1/Sp1CTDp (DDM)
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DODECAETHYLENE GLYCOL, DODECANE, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-14
Release date:2022-06-15
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (4.194 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
3DNK
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BU of 3dnk by Molmil
Enzyme deglycosylated Human IgG1 Fc fragment
Descriptor: IGHM protein
Authors:Braden, B.C.
Deposit date:2008-07-02
Release date:2009-07-21
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:2.8 Angstrom structure of a enzyme deglycosylated human IgG1 Fc fragment
To be Published
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
5N86
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BU of 5n86 by Molmil
Crystal structure of FAS1 domain of hyaluronic acid receptor stabilin-2
Descriptor: Stabilin-2
Authors:Twarda-Clapa, A, Labuzek, B, Grudnik, P, Dubin, G, Holak, T.A.
Deposit date:2017-02-23
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.484 Å)
Cite:Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2.
Acta Crystallogr D Struct Biol, 74, 2018
7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
5M33
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BU of 5m33 by Molmil
Structural tuning of CD81LEL (space group P21)
Descriptor: 1,2-ETHANEDIOL, CD81 antigen
Authors:Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G.
Deposit date:2016-10-14
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017

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數據於2024-07-31公開中

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