2RHP
The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure
Summary for 2RHP
| Entry DOI | 10.2210/pdb2rhp/pdb |
| Related | 1YO8 |
| Descriptor | Thrombospondin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | extracellular matrix, calcium-binding, glycosylated, jelly-roll, egf-like, lectin-like, cell adhesion, egf-like domain, glycoprotein, heparin-binding |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 71368.64 |
| Authors | Carlson, C.B.,Keck, J.L.,Mosher, D.F. (deposition date: 2007-10-09, release date: 2008-05-27, Last modification date: 2023-08-30) |
| Primary citation | Carlson, C.B.,Liu, Y.,Keck, J.L.,Mosher, D.F. Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability. J.Biol.Chem., 283:20069-20076, 2008 Cited by PubMed: 18499674DOI: 10.1074/jbc.M800223200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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