6AOT
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 6'-SLNLN
Summary for 6AOT
Entry DOI | 10.2210/pdb6aot/pdb |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | influenza a virus, hemagglutinin, mutant, receptor binding, antigenicity, viral protein |
Biological source | Influenza A virus (A/Brisbane/10/2007(H3N2)) More |
Total number of polymer chains | 2 |
Total formula weight | 58993.49 |
Authors | Wu, N.C.,Wilson, I.A. (deposition date: 2017-08-16, release date: 2017-10-18, Last modification date: 2023-10-04) |
Primary citation | Wu, N.C.,Zost, S.J.,Thompson, A.J.,Oyen, D.,Nycholat, C.M.,McBride, R.,Paulson, J.C.,Hensley, S.E.,Wilson, I.A. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13:e1006682-e1006682, 2017 Cited by PubMed: 29059230DOI: 10.1371/journal.ppat.1006682 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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