8FSJ
| Cryo-EM structure of engineered hepatitis C virus E1E2 ectodomain in complex with antibodies AR4A, HEPC74, and IGH520 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A heavy chain, ... | Authors: | Metcalf, M.C, Ofek, G. | Deposit date: | 2023-01-10 | Release date: | 2023-07-19 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies. Nat Commun, 14, 2023
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8OIF
| Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6 | Descriptor: | ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... | Authors: | Wallace, I, Kheewoong, B, Prabu, J.R, Vollrath, R, von Gronau, S, Schulman, B.A, Swatek, K.N. | Deposit date: | 2023-03-22 | Release date: | 2023-12-13 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Insights into the ISG15 transfer cascade by the UBE1L activating enzyme. Nat Commun, 14, 2023
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8G4C
| BceABS ATPgS high res TM | Descriptor: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | George, N.L, Orlando, B.J. | Deposit date: | 2023-02-09 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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4BW9
| PylRS Y306G, Y384F, I405R mutant in complex with AMP-PNP | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Schneider, S, Vrabel, M, Gattner, M.J, Fluegel, V, Lopez-Carillo, V, Carell, T. | Deposit date: | 2013-07-01 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Insights Into Incorporation of Norbornene Amino Acids for Click Modification of Proteins Chem.Bio.Chem., 14, 2013
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8E3S
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8OH7
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8G1A
| Cryo-EM structure of Nav1.7 with CBD | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2023-02-01 | Release date: | 2023-07-05 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cannabidiol inhibits Na v channels through two distinct binding sites. Nat Commun, 14, 2023
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8G3F
| BceAB-S nucleotide free BceS state 1 | Descriptor: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | Authors: | George, N.L, Orlando, B.J. | Deposit date: | 2023-02-07 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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8FZY
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2J44
| Alpha-glucan binding by a streptococcal virulence factor | Descriptor: | ALKALINE AMYLOPULLULANASE, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Lammerts van Bueren, A, Higgins, M, Wang, D, Burke, R.D, Boraston, A.B. | Deposit date: | 2006-08-24 | Release date: | 2006-12-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification and Structural Basis of Binding to Host Lung Glycogen by Streptococcal Virulence Factors. Nat.Struct.Mol.Biol., 14, 2007
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8KAD
| Crystal structure of an antibody light chain tetramer with 3D domain swapping | Descriptor: | Antibody light chain | Authors: | Sakai, T, Mashima, T, Kobayashi, N, Ogata, H, Uda, T, Hifumi, E, Hirota, S. | Deposit date: | 2023-08-02 | Release date: | 2023-12-27 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nat Commun, 14, 2023
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8G0K
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4BR3
| Determination of potential scaffolds for human choline kinase alpha 1 by chemical deconvolution studies | Descriptor: | 1-((4'-((6-amino-3H-purin-3-yl)methyl)biphenyl-4-yl)methyl)-4-(dimethylamino)pyridinium, 3-benzyladenine, CHOLINE KINASE ALPHA, ... | Authors: | Sahun-Roncero, M, Rubio-Ruiz, B, Conejo-Garcia, A, Velazquez-Campoy, A, Entrena, A, Hurtado-Guerrero, R. | Deposit date: | 2013-06-03 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Determination of Potential Scaffolds for Human Choline Kinase Alpha 1 by Chemical Deconvolution Studies Chembiochem, 14, 2013
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8GI4
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8GW6
| AtSLAC1 6D mutant in closed state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | Authors: | Lee, Y, Lee, S. | Deposit date: | 2022-09-16 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GJ4
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8GLC
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8GIC
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8GJP
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8E4V
| Solution structure of the WH domain of MORF | Descriptor: | Isoform 3 of Histone acetyltransferase KAT6B | Authors: | Zhang, Y, Kutateladze, T.G. | Deposit date: | 2022-08-19 | Release date: | 2023-05-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain. Nat Commun, 14, 2023
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8E7Q
| Crystal Structure of FosB from Bacillus cereus with Zinc and 2-Phosphonopropionic acid | Descriptor: | (2S)-2-phosphonopropanoic acid, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Travis, S, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2022-08-24 | Release date: | 2023-06-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8DWJ
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8E7R
| Crystal Structure of FosB from Bacillus cereus with Zinc and Phosphonoacetate | Descriptor: | FORMIC ACID, MAGNESIUM ION, Metallothiol transferase FosB, ... | Authors: | Travis, S, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2022-08-24 | Release date: | 2023-06-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8E8R
| 9H2 Fab-Sabin poliovirus 3 complex | Descriptor: | 9H2 Fab heavy chain, 9H2 Fab light chain, Capsid protein VP1, ... | Authors: | Charnesky, A.J. | Deposit date: | 2022-08-25 | Release date: | 2023-06-21 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | A human monoclonal antibody binds within the poliovirus receptor-binding site to neutralize all three serotypes. Nat Commun, 14, 2023
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8KI1
| Crystal structure of the holo form of the hemophore HasA from Pseudomonas protegens Pf-5 | Descriptor: | GLYCEROL, Heme acquisition protein HasAp, PHOSPHATE ION, ... | Authors: | Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O. | Deposit date: | 2023-08-22 | Release date: | 2024-03-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. Rsc Adv, 14, 2024
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