8E7Q

Crystal Structure of FosB from Bacillus cereus with Zinc and 2-Phosphonopropionic acid

Summary for 8E7Q

Entry DOI	10.2210/pdb8e7q/pdb
Descriptor	Metallothiol transferase FosB, (2S)-2-phosphonopropanoic acid, FORMIC ACID, ... (6 entities in total)
Functional Keywords	inhibitor, 2-phosphonopropionic acid, transferase
Biological source	Bacillus cereus
Total number of polymer chains	2
Total formula weight	33510.54
Authors	Travis, S.,Tsodikov, O.V.,Garneau-Tsodikova, S.,Thompson, M.K. (deposition date: 2022-08-24, release date: 2023-06-14, Last modification date: 2023-10-25)
Primary citation	Travis, S.,Green, K.D.,Thamban Chandrika, N.,Pang, A.H.,Frantom, P.A.,Tsodikov, O.V.,Garneau-Tsodikova, S.,Thompson, M.K. Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14:947-956, 2023 Cited by PubMed: 37252104 DOI: 10.1039/d3md00113j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation