5IF8
 
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7ZNV
 
 | Artificial Unspecific Peroxygenase expressed in Pichia pastoris at 1.21 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | Authors: | Robinson, W.X.Q, Mielke, T, Grogan, G. | Deposit date: | 2022-04-22 | Release date: | 2023-03-01 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Comparing the Catalytic and Structural Characteristics of a 'Short' Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli. Chembiochem, 24, 2023
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8VO2
 
 | Pathogenesis related 10-10 C59S mutant | Descriptor: | Pathogenesis related 10-10 C59S mutant | Authors: | Carr, S.C, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2024-01-14 | Release date: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural analysis of a ligand-triggered intermolecular disulfide switch in a major latex protein from opium poppy. Acta Crystallogr D Struct Biol, 80, 2024
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5I55
 
 | Crystal Structure of the Virulent PSM-alpha3 Peptide Forming a Cross-alpha amyloid-like Fibril | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Psm alpha-3 | Authors: | Landau, M, Moshe, A, Tayeb-Fligelman, E, Sawaya, M.R, Coquelle, N, Colletier, J.-P. | Deposit date: | 2016-02-14 | Release date: | 2017-03-01 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The cytotoxic Staphylococcus aureus PSM alpha 3 reveals a cross-alpha amyloid-like fibril. Science, 355, 2017
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8VO1
 
 | Pathogenesis related 10-10 C155S mutant | Descriptor: | Pathogenesis related 10-10 C155S mutant | Authors: | Carr, S.C, Facchini, P.J, Ng, K.K.S. | Deposit date: | 2024-01-14 | Release date: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of a ligand-triggered intermolecular disulfide switch in a major latex protein from opium poppy. Acta Crystallogr D Struct Biol, 80, 2024
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8VPA
 
 | Cryo-EM structure of the ABC transporter PCAT1 bound with ADP | Descriptor: | ABC-type bacteriocin transporter, ADENOSINE-5'-DIPHOSPHATE | Authors: | Zhang, R, Jagessar, K.L, Polasa, A, Brownd, M, Stein, R, Moradi, M, Karakas, E, Mchaourab, H.S. | Deposit date: | 2024-01-16 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling. Nat Commun, 15, 2024
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6VMV
 
 | Crystal structure of the H767A mutant of GoxA soaked with glycine | Descriptor: | Glycine oxidase, MAGNESIUM ION, SULFATE ION | Authors: | Yukl, E.T. | Deposit date: | 2020-01-28 | Release date: | 2020-04-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Roles of active-site residues in catalysis, substrate binding, cooperativity, and the reaction mechanism of the quinoprotein glycine oxidase. J.Biol.Chem., 295, 2020
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7LW0
 
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5IFS
 
 | Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Roske, Y, Arumughan, A, Heinemann, U, Wanker, E. | Deposit date: | 2016-02-26 | Release date: | 2016-10-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers. Nat Commun, 7, 2016
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8W2Q
 
 | BsaXI-DNA complex II | Descriptor: | DNA (41-MER), RM.BsaXI, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Shen, B.W, Stoddard, B.L, Xu, S. | Deposit date: | 2024-02-21 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural and biochemical analysis of subunit assembly, DNA recognition and cleavage by a Type IIB restriction-modification enzyme: BsaXI To Be Published
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7LV5
 
 | The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, BICINE, ... | Authors: | Hilario, E, Dunn, M.F, Mueller, L.J. | Deposit date: | 2021-02-23 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution To be Published
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5IG2
 
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8VPB
 
 | Cryo-EM structure of the ABC transporter PCAT1 bound with MgADP_Class_2 | Descriptor: | ABC-type bacteriocin transporter, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Zhang, R, Jagessar, K.L, Polasa, A, Brownd, M, Stein, R, Moradi, M, Karakas, E, Mchaourab, H.S. | Deposit date: | 2024-01-16 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling. Nat Commun, 15, 2024
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5VJV
 
 | Rhizobiales-like phosphatase 2 | Descriptor: | PHOSPHATE ION, Rhizobiales-like phosphatase 2, ZINC ION | Authors: | Ng, K.K.S, Labandera, A, Moorhead, G. | Deposit date: | 2017-04-20 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the preference of the Arabidopsis thalianaphosphatase RLPH2 for tyrosine-phosphorylated substrates. Sci Signal, 11, 2018
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6VNX
 
 | Crystal structure of TYK2 kinase with compound 19 | Descriptor: | (1S)-2,2-difluoro-N-[(1S,5R,6R)-3-{5-fluoro-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-6-methyl-3-azabicyclo[3.1.0]hexan-1-yl]cyclopropane-1-carboxamide, Non-receptor tyrosine-protein kinase TYK2 | Authors: | Vajdos, F.F. | Deposit date: | 2020-01-29 | Release date: | 2020-04-08 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1. Bioorg.Med.Chem., 28, 2020
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8W2P
 
 | BsaXI-DNA complex I | Descriptor: | CALCIUM ION, DNA (41-MER) Complementary strand of BsaXI DNA substrate, DNA (41-MER) Top strand of BsaXI cognate DNA substrate, ... | Authors: | Shen, B.W, Stoddard, B.L, Xu, S. | Deposit date: | 2024-02-20 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structural and biochemical analysis of subunit assembly, DNA recognition and cleavage by a Type IIB restriction-modification enzyme: BsaXI To Be Published
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5I5X
 
 | X-RAY CRYSTAL STRUCTURE AT 1.65A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A THIAZOLE COMPOUND AND PMP COFACTOR. | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 5-methyl-4-oxo-N-(1,3,4-thiadiazol-2-yl)-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamide, ... | Authors: | Somers, D.O. | Deposit date: | 2016-02-15 | Release date: | 2016-03-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening. J.Med.Chem., 59, 2016
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6VO2
 
 | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg, NADPH and inhibitor. | Descriptor: | 3-(methylsulfonyl)-2-oxopropanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ... | Authors: | Bayaraa, T, Patel, K.M, Guddat, L.W. | Deposit date: | 2020-01-29 | Release date: | 2020-04-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor. Chemistry, 26, 2020
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8VGQ
 
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5IGJ
 
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6VIL
 
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7LX1
 
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8VWT
 
 | OGG1 bound to a nucleosome containing 8oxoG at SHL-6 (composite map) | Descriptor: | 601 I strand (non-damaged strand), 601 J strand (damaged strand), Histone H2A type 1, ... | Authors: | Weaver, T.M, Ling, J.A, Freudenthal, B.D. | Deposit date: | 2024-02-02 | Release date: | 2024-10-30 | Last modified: | 2025-01-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Contributing factors to the oxidation-induced mutational landscape in human cells. Nat Commun, 15, 2024
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5VKO
 
 | SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, ISOPROPYL ALCOHOL, Transcription elongation factor SPT6 | Authors: | Sdano, M.A, Whitby, F.G, Hill, C.P. | Deposit date: | 2017-04-21 | Release date: | 2017-09-20 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife, 6, 2017
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5IGW
 
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