4V08
Inhibited dimeric pseudorabies virus protease pUL26N at 2 A resolution
Summary for 4V08
Entry DOI | 10.2210/pdb4v08/pdb |
Related | 4CX8 4V07 4V0T |
Descriptor | UL26, DIISOPROPYL PHOSPHONATE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | viral protein, assemblin, ul26, ul26p, serine protease, protease, suid, prv, herpes, herpes virus |
Biological source | SUID HERPESVIRUS 1 (PSEUDORABIES VIRUS) |
Cellular location | Capsid scaffolding protein: Host cytoplasm . Assemblin: Host nucleus . Assembly protein: Host nucleus : Q83417 |
Total number of polymer chains | 2 |
Total formula weight | 53753.69 |
Authors | Zuehlsdorf, M.,Werten, S.,Palm, G.J.,Hinrichs, W. (deposition date: 2014-09-11, release date: 2015-07-15, Last modification date: 2024-01-10) |
Primary citation | Zuehlsdorf, M.,Werten, S.,Klupp, B.G.,Palm, G.J.,Mettenleiter, T.,Hinrichs, W. Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease Plos Pathog., 11:5045-, 2015 Cited by PubMed: 26161660DOI: 10.1371/JOURNAL.PPAT.1005045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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