4Q69
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7MXO
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![BU of 7mxo by Molmil](/molmil-images/mine/7mxo) | CryoEM structure of human NKCC1 | Descriptor: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-05-19 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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2ZNB
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![BU of 2znb by Molmil](/molmil-images/mine/2znb) | METALLO-BETA-LACTAMASE (CADMIUM-BOUND FORM) | Descriptor: | CADMIUM ION, METALLO-BETA-LACTAMASE, SODIUM ION | Authors: | Concha, N.O, Herzberg, O. | Deposit date: | 1997-10-14 | Release date: | 1998-01-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of the cadmium- and mercury-substituted metallo-beta-lactamase from Bacteroides fragilis. Protein Sci., 6, 1997
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2ZSG
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7JSJ
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![BU of 7jsj by Molmil](/molmil-images/mine/7jsj) | Structure of the NaCT-PF2 complex | Descriptor: | (2R)-2-[2-(4-tert-butylphenyl)ethyl]-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | Authors: | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | Deposit date: | 2020-08-14 | Release date: | 2021-02-24 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structure and inhibition mechanism of the human citrate transporter NaCT. Nature, 591, 2021
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7NBG
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![BU of 7nbg by Molmil](/molmil-images/mine/7nbg) | Crystal structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen. | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | Authors: | Koulouris, C.R, Roe, S.M. | Deposit date: | 2021-01-26 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBH
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![BU of 7nbh by Molmil](/molmil-images/mine/7nbh) | Crystal structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen. | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Koulouris, C.R, Roe, S.M. | Deposit date: | 2021-01-26 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7JSK
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![BU of 7jsk by Molmil](/molmil-images/mine/7jsk) | Structure of the NaCT-Citrate complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, SODIUM ION, ... | Authors: | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | Deposit date: | 2020-08-14 | Release date: | 2021-02-24 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structure and inhibition mechanism of the human citrate transporter NaCT. Nature, 591, 2021
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6XFR
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7NBC
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![BU of 7nbc by Molmil](/molmil-images/mine/7nbc) | Crystal structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen. | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | Authors: | Koulouris, C.R, Roe, S.M. | Deposit date: | 2021-01-26 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBF
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![BU of 7nbf by Molmil](/molmil-images/mine/7nbf) | Crystal structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen. | Descriptor: | 1,2-ETHANEDIOL, 2-[(methylsulfonyl)methyl]-1H-benzimidazole, CALCIUM ION, ... | Authors: | Koulouris, C.R, Roe, S.M. | Deposit date: | 2021-01-26 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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6XNL
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7SFL
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![BU of 7sfl by Molmil](/molmil-images/mine/7sfl) | Human NKCC1 state Fu-II | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-04 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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7SMP
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![BU of 7smp by Molmil](/molmil-images/mine/7smp) | CryoEM structure of NKCC1 Bu-I | Descriptor: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-26 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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8U9B
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6Y72
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![BU of 6y72 by Molmil](/molmil-images/mine/6y72) | Pseudomonas stutzeri nitrous oxide reductase mutant, H178A | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Zhang, L, Kroneck, P.M.H, Einsle, O. | Deposit date: | 2020-02-27 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase. Chem Sci, 12, 2021
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8TS5
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![BU of 8ts5 by Molmil](/molmil-images/mine/8ts5) | Structure of the apo FabS1C_C1 | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | Authors: | Singer, A.U, Bruce, H.A, Blazer, L.L, Adams, J.J, Sicheri, F, Sidhu, S.S. | Deposit date: | 2023-08-10 | Release date: | 2023-11-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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8TRS
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![BU of 8trs by Molmil](/molmil-images/mine/8trs) | Structure of the EphA2 CRD bound to FabS1CE_C1, trigonal form | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | Deposit date: | 2023-08-10 | Release date: | 2023-11-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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6YBZ
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![BU of 6ybz by Molmil](/molmil-images/mine/6ybz) | Crystal structure of the D116N mutant of the light-driven sodium pump KR2 in the pentameric form, pH 8.0 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, RETINAL, ... | Authors: | Kovalev, K, Gushchin, I, Gordeliy, V. | Deposit date: | 2020-03-18 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular mechanism of light-driven sodium pumping. Nat Commun, 11, 2020
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6YHN
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![BU of 6yhn by Molmil](/molmil-images/mine/6yhn) | Crystal structure of domains 4-5 of CNFy from Yersinia pseudotuberculosis | Descriptor: | (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, Cytotoxic necrotizing factor, ... | Authors: | Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. | Deposit date: | 2020-03-30 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
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7NPI
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![BU of 7npi by Molmil](/molmil-images/mine/7npi) | Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5) | Descriptor: | CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... | Authors: | Lange, S.M, Armstrong, L.A, Kulathu, Y. | Deposit date: | 2021-02-26 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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5TCD
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![BU of 5tcd by Molmil](/molmil-images/mine/5tcd) | Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gorelik, A, Liu, F, Illes, K, Nagar, B. | Deposit date: | 2016-09-14 | Release date: | 2017-03-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. J. Biol. Chem., 292, 2017
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6Y71
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![BU of 6y71 by Molmil](/molmil-images/mine/6y71) | Pseudomonas stutzeri nitrous oxide reductase mutant, H130A | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Zhang, L, Kroneck, P.M.H, Einsle, O. | Deposit date: | 2020-02-27 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase. Chem Sci, 12, 2021
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5UD1
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6YC3
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![BU of 6yc3 by Molmil](/molmil-images/mine/6yc3) | Crystal structure of the light-driven sodium pump KR2 in the pentameric form, pH 8.0 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, RETINAL, ... | Authors: | Kovalev, K, Gushchin, I, Gordeliy, V. | Deposit date: | 2020-03-18 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular mechanism of light-driven sodium pumping. Nat Commun, 11, 2020
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