7NBC
Crystal structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen.
This is a non-PDB format compatible entry.
Summary for 7NBC
Entry DOI | 10.2210/pdb7nbc/pdb |
Related | 6ZSP 6ZUJ |
Descriptor | Serine racemase, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... (10 entities in total) |
Functional Keywords | racemase, xchem, inhibitor, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 153067.07 |
Authors | Koulouris, C.R.,Roe, S.M. (deposition date: 2021-01-26, release date: 2021-03-03, Last modification date: 2024-01-31) |
Primary citation | Koulouris, C.R.,Gardiner, S.E.,Harris, T.K.,Elvers, K.T.,Mark Roe, S.,Gillespie, J.A.,Ward, S.E.,Grubisha, O.,Nicholls, R.A.,Atack, J.R.,Bax, B.D. Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5:346-346, 2022 Cited by PubMed: 35410329DOI: 10.1038/s42003-022-03264-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
Download full validation report