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7NBC

Crystal structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(AAA, BBB, CCC, DDD)
Serine racemasepolymer34637455.94UniProt (Q9GZT4)
Pfam (PF00291)
Homo sapiens (Human)D-serine ammonia-lyase,D-serine dehydratase,L-serine ammonia-lyase,L-serine dehydratase
2AA, E, IA, S
(CCC, AAA, DDD, BBB)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.14Chemie (PLP)D-serine ammonia-lyase,D-serine dehydratase,L-serine ammonia-lyase,L-serine dehydratase
3BA, F, G, HA, J...
(CCC, AAA, BBB)
GLYCEROLnon-polymer92.110Chemie (GOL)
4CA, H, JA, O, U...
(CCC, AAA, DDD, BBB)
CALCIUM IONnon-polymer40.16Chemie (CA)
5I, KA
(AAA, DDD)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6FA, GA, K, L, MA...
(CCC, AAA, DDD, BBB)
1,2-ETHANEDIOLnon-polymer62.110Chemie (EDO)
7LA, P, Q, R
(DDD, AAA)
SODIUM IONnon-polymer23.04Chemie (NA)
8DA
(CCC)
2-(2-METHOXYETHOXY)ETHANOLnon-polymer120.11Chemie (PG0)
9EA
(CCC)
biphenyl-4-ylacetic acidnon-polymer212.21Chemie (BP4)
10QA, RA, SA, TA
(AAA, BBB, CCC, DDD)
waterwater18.0867Chemie (HOH)
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 340 (UniProt: Q9GZT4)
PDBExternal DatabaseDetails
Asp 2Cys 2engineered mutation
Asp 6Cys 6engineered mutation
His 341-expression tag
His 342-expression tag
His 343-expression tag
His 344-expression tag
His 345-expression tag
His 346-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight149823.5
Non-Polymers*Number of molecules38
Total formula weight3243.6
All*Total formula weight153067.1
*Water molecules are not included.

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PDB entries from 2025-07-02

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