7NBF

Crystal structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen.

This is a non-PDB format compatible entry.

Summary for 7NBF

• Entry DOI: 10.2210/pdb7nbf/pdb
• Related: 6ZSP 6ZUJ
• Descriptor: Serine racemase, TRIETHYLENE GLYCOL, CHLORIDE ION, ... (12 entities in total)
• Functional Keywords: racemase, xchem, inhibitor, isomerase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 153472.47

Authors

Koulouris, C.R.,Roe, S.M. (deposition date: 2021-01-26, release date: 2021-03-03, Last modification date: 2024-01-31)

• Primary citation: Koulouris, C.R.,Gardiner, S.E.,Harris, T.K.,Elvers, K.T.,Mark Roe, S.,Gillespie, J.A.,Ward, S.E.,Grubisha, O.,Nicholls, R.A.,Atack, J.R.,Bax, B.D.; Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.; Commun Biol, 5:346-346, 2022; PubMed: 35410329; DOI: 10.1038/s42003-022-03264-5

Experimental method

X-RAY DIFFRACTION (1.6 Å)