Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2L14
DownloadVisualize
BU of 2l14 by Molmil
Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
Descriptor: CREB-binding protein, Cellular tumor antigen p53
Authors:Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2010-07-22
Release date:2010-11-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
2L4Z
DownloadVisualize
BU of 2l4z by Molmil
NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82)
Descriptor: DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION
Authors:Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M.
Deposit date:2010-10-22
Release date:2011-10-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8.
J.Mol.Biol., 425, 2013
2YT4
DownloadVisualize
BU of 2yt4 by Molmil
Crystal structure of human DGCR8 core
Descriptor: Protein DGCR8
Authors:Cho, Y, Sohn, S.Y.
Deposit date:2007-04-05
Release date:2007-08-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human DGCR8 core
Nat.Struct.Mol.Biol., 14, 2007
2RP3
DownloadVisualize
BU of 2rp3 by Molmil
Solution Structure of Cyanovirin-N Domain B Mutant
Descriptor: Cyanovirin-N
Authors:Matei, E, Furey, W, Gronenborn, A.M.
Deposit date:2008-04-30
Release date:2008-08-19
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping
Structure, 16, 2008
2Z5T
DownloadVisualize
BU of 2z5t by Molmil
Molecular basis for the inhibition of p53 by Mdmx
Descriptor: Cellular tumor antigen p53, Mdm4 protein
Authors:Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A.
Deposit date:2007-07-17
Release date:2007-11-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007
2U2A
DownloadVisualize
BU of 2u2a by Molmil
STEM LOOP IIA FROM U2 SNRNA OF SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RNA (5'-R(P*GP*GP*UP*CP*AP*GP*UP*GP*UP*AP*AP*CP*AP*AP*CP*UP*GP*AP*CP*C)-3')
Authors:Stallings, S.C, Moore, P.B.
Deposit date:1997-08-20
Release date:1998-03-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA.
Structure, 5, 1997
2VJF
DownloadVisualize
BU of 2vjf by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
Descriptor: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
Authors:Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
Deposit date:2007-12-10
Release date:2008-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
Cell Death Differ., 15, 2008
2VJE
DownloadVisualize
BU of 2vje by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
Descriptor: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
Authors:Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
Deposit date:2007-12-10
Release date:2008-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Cell Death Differ., 15, 2008
2W0J
DownloadVisualize
BU of 2w0j by Molmil
Crystal structure of Chk2 in complex with NSC 109555, a specific inhibitor
Descriptor: 4,4'-DIACETYLDIPHENYLUREA-BIS(GUANYLHYDRAZONE), NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2
Authors:Lountos, G.T, Tropea, J.E, Zhang, D, Jobson, A.G, Pommier, Y, Shoemaker, R.H, Waugh, D.S.
Deposit date:2008-08-18
Release date:2009-02-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of Checkpoint Kinase 2 in Complex with Nsc 109555, a Potent and Selective Inhibitor
Protein Sci., 18, 2009
3I6W
DownloadVisualize
BU of 3i6w by Molmil
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Descriptor: Serine/threonine-protein kinase Chk2
Authors:Pavletich, N.P.
Deposit date:2009-07-07
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
3I6U
DownloadVisualize
BU of 3i6u by Molmil
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Descriptor: Serine/threonine-protein kinase Chk2
Authors:Pavletich, N.P.
Deposit date:2009-07-07
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
3J9T
DownloadVisualize
BU of 3j9t by Molmil
Yeast V-ATPase state 1
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
3J9U
DownloadVisualize
BU of 3j9u by Molmil
Yeast V-ATPase state 2
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
3K2L
DownloadVisualize
BU of 3k2l by Molmil
Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2)
Descriptor: CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ...
Authors:Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2009-09-30
Release date:2009-10-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Structure, 21, 2013
2XVS
DownloadVisualize
BU of 2xvs by Molmil
Crystal structure of human TTC5 (Strap) C-terminal OB domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, IODIDE ION, ...
Authors:Adams, J, Pike, A.C.W, Maniam, S, Sharpe, T.D, Coutts, A.S, Knapp, S, La Thangue, B, Bullock, A.N.
Deposit date:2010-10-31
Release date:2010-11-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure.
Proc.Natl.Acad.Sci.USA, 109, 2012
2WTI
DownloadVisualize
BU of 2wti by Molmil
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
Descriptor: 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ...
Authors:Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I.
Deposit date:2009-09-16
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
3J9V
DownloadVisualize
BU of 3j9v by Molmil
Yeast V-ATPase state 3
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
2Z5S
DownloadVisualize
BU of 2z5s by Molmil
Molecular basis for the inhibition of p53 by Mdmx
Descriptor: Cellular tumor antigen p53, Mdm4 protein
Authors:Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A.
Deposit date:2007-07-17
Release date:2007-11-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007
2WTJ
DownloadVisualize
BU of 2wtj by Molmil
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ...
Authors:Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I.
Deposit date:2009-09-16
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
3BU8
DownloadVisualize
BU of 3bu8 by Molmil
Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex
Descriptor: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2
Authors:Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BRV
DownloadVisualize
BU of 3brv by Molmil
NEMO/IKKb association domain structure
Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta, NF-kappa-B essential modulator
Authors:Silvian, L.F.
Deposit date:2007-12-21
Release date:2008-04-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site.
Structure, 16, 2008
3BUA
DownloadVisualize
BU of 3bua by Molmil
Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex
Descriptor: DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2
Authors:Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
1GGW
DownloadVisualize
BU of 1ggw by Molmil
CDC4P FROM SCHIZOSACCHAROMYCES POMBE
Descriptor: PROTEIN (CDC4P)
Authors:Slupsky, C.M, Hemmingsen, S.M, McIntosh, L.P.
Deposit date:2000-09-25
Release date:2001-03-21
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe.
J.Biol.Chem., 276, 2001
5VOX
DownloadVisualize
BU of 5vox by Molmil
Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 1)
Descriptor: V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J.
Deposit date:2017-05-03
Release date:2017-06-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VZT
DownloadVisualize
BU of 5vzt by Molmil
Crystal structure of the Skp1-FBXO31 complex
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ...
Authors:Li, Y, Jin, K, Hao, B.
Deposit date:2017-05-29
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

221051

數據於2024-06-12公開中

PDB statisticsPDBj update infoContact PDBjnumon