1AXI
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![BU of 1axi by Molmil](/molmil-images/mine/1axi) | STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE | Descriptor: | GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION | Authors: | Atwell, S, Ultsch, M, De Vos, A.M, Wells, J.A. | Deposit date: | 1997-10-15 | Release date: | 1998-01-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural plasticity in a remodeled protein-protein interface. Science, 278, 1997
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1ZLG
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![BU of 1zlg by Molmil](/molmil-images/mine/1zlg) | Solution structure of the extracellular matrix protein anosmin-1 | Descriptor: | Anosmin 1 | Authors: | Hu, Y, Sun, Z, Eaton, J.T, Bouloux, P.M, Perkins, S.J. | Deposit date: | 2005-05-06 | Release date: | 2006-05-09 | Last modified: | 2024-05-22 | Method: | SOLUTION SCATTERING | Cite: | Extended and Flexible Domain Solution Structure of the Extracellular Matrix Protein Anosmin-1 by X-ray Scattering, Analytical Ultracentrifugation and Constrained Modelling. J.Mol.Biol., 350, 2005
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1I1R
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![BU of 1i1r by Molmil](/molmil-images/mine/1i1r) | CRYSTAL STRUCTURE OF A CYTOKINE/RECEPTOR COMPLEX | Descriptor: | INTERLEUKIN-6 RECEPTOR BETA CHAIN, VIRAL IL-6 | Authors: | Chow, D, He, X, Snow, A.L, Rose-John, S, Garcia, K.C. | Deposit date: | 2001-02-02 | Release date: | 2001-03-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of an extracellular gp130 cytokine receptor signaling complex. Science, 291, 2001
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2AEW
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![BU of 2aew by Molmil](/molmil-images/mine/2aew) | |
2X10
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![BU of 2x10 by Molmil](/molmil-images/mine/2x10) | Crystal structure of the complete EphA2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2 | Authors: | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2009-12-21 | Release date: | 2010-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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7TYJ
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![BU of 7tyj by Molmil](/molmil-images/mine/7tyj) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied | Descriptor: | Insulin receptor-related protein | Authors: | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYK
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![BU of 7tyk by Molmil](/molmil-images/mine/7tyk) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry | Descriptor: | Insulin receptor-related protein | Authors: | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYM
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![BU of 7tym by Molmil](/molmil-images/mine/7tym) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry | Descriptor: | Insulin receptor-related protein | Authors: | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | Deposit date: | 2022-02-13 | Release date: | 2023-02-15 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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2XYC
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![BU of 2xyc by Molmil](/molmil-images/mine/2xyc) | CRYSTAL STRUCTURE OF NCAM2 IGIV-FN3I | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NEURAL CELL ADHESION MOLECULE 2, ... | Authors: | Kulahin, N, Rasmussen, K.K, Kristensen, O, Berezin, V, Bock, E, Walmod, P.S, Gajhede, M. | Deposit date: | 2010-11-17 | Release date: | 2011-02-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule. Structure, 19, 2011
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6P67
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![BU of 6p67 by Molmil](/molmil-images/mine/6p67) | Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ... | Authors: | Walsh, S.T.R, Kashi, L, Kohnhorst, C.L. | Deposit date: | 2019-06-03 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia, 34, 2020
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6P50
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![BU of 6p50 by Molmil](/molmil-images/mine/6p50) | Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ... | Authors: | Walsh, S.T.R, Kashi, L, Kohnhorst, C.L. | Deposit date: | 2019-05-29 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia, 34, 2020
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2W1N
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![BU of 2w1n by Molmil](/molmil-images/mine/2w1n) | cohesin and fibronectin type-III double module construct from the Clostridium perfringens glycoside hydrolase GH84C | Descriptor: | ACETATE ION, O-GLCNACASE NAGJ | Authors: | Ficko-Blean, E, Gregg, K.J, Adams, J.J, Hehemann, J.H, Czjzek, M, Smith, S.J, Boraston, A.B. | Deposit date: | 2008-10-17 | Release date: | 2009-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Portrait of an Enzyme: A Complete Structural Analysis of a Multi-Modular Beta-N-Acetylglucosaminidase from Clostridium Perfringens J.Biol.Chem., 284, 2009
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2X11
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![BU of 2x11 by Molmil](/molmil-images/mine/2x11) | Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain | Descriptor: | EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5 | Authors: | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2009-12-21 | Release date: | 2010-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.83 Å) | Cite: | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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5N47
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![BU of 5n47 by Molmil](/molmil-images/mine/5n47) | |
1P9M
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![BU of 1p9m by Molmil](/molmil-images/mine/1p9m) | Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex | Descriptor: | Interleukin-6, Interleukin-6 receptor alpha chain, Interleukin-6 receptor beta chain | Authors: | Boulanger, M.J, Chow, D.C, Brevnova, E.E, Garcia, K.C. | Deposit date: | 2003-05-12 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Hexameric Structure and Assembly of the Interleukin-6/IL-6 alpha-Receptor/gp130 Complex Science, 300, 2003
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6POL
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![BU of 6pol by Molmil](/molmil-images/mine/6pol) | Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Wang, J, Pak, J.S, Ozkan, E. | Deposit date: | 2019-07-04 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun, 11, 2020
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5N48
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7U6E
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![BU of 7u6e by Molmil](/molmil-images/mine/7u6e) | |
6POG
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![BU of 6pog by Molmil](/molmil-images/mine/6pog) | Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wang, J, Pak, J.S, Ozkan, E. | Deposit date: | 2019-07-03 | Release date: | 2020-05-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.755 Å) | Cite: | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun, 11, 2020
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6PXV
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![BU of 6pxv by Molmil](/molmil-images/mine/6pxv) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. | Descriptor: | Insulin, Insulin receptor | Authors: | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | Deposit date: | 2019-07-27 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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7U6D
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7U7N
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![BU of 7u7n by Molmil](/molmil-images/mine/7u7n) | IL-27 quaternary receptor signaling complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | Authors: | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | Deposit date: | 2022-03-07 | Release date: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
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6PXW
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![BU of 6pxw by Molmil](/molmil-images/mine/6pxw) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex. | Descriptor: | Insulin, Insulin receptor | Authors: | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | Deposit date: | 2019-07-28 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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1HWH
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1HWG
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![BU of 1hwg by Molmil](/molmil-images/mine/1hwg) | |