6POG

Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex

Summary for 6POG

• Entry DOI: 10.2210/pdb6pog/pdb
• Descriptor: Roundabout homolog 3, Protein kinase C-binding protein NELL2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: axon guidance, nervous system, heterodimeric complex, glycoprotein, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 40542.66

Authors

Wang, J.,Pak, J.S.,Ozkan, E. (deposition date: 2019-07-03, release date: 2020-05-06, Last modification date: 2020-07-29)

• Primary citation: Pak, J.S.,DeLoughery, Z.J.,Wang, J.,Acharya, N.,Park, Y.,Jaworski, A.,Ozkan, E.; NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.; Nat Commun, 11:1489-1489, 2020; PubMed: 32198364; DOI: 10.1038/s41467-020-15211-1

Experimental method

X-RAY DIFFRACTION (2.755 Å)