6POG

Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Roundabout homolog 3	polymer	114	12145.4	1	UniProt (Q96MS0) Pfam (PF00041)	Homo sapiens (Human)	Roundabout-like protein 3
2	B (B)	Protein kinase C-binding protein NELL2	polymer	249	27485.3	1	UniProt (Q99435) Pfam (PF07645) Pfam (PF12947)	Homo sapiens (Human)	NEL-like protein 2,Nel-related protein 2
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
4	D (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	E, F, G (B)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)

Sequence modifications

A: 551 - 663 (UniProt: Q96MS0)

PDB	External Database	Details
Ala 550	-	expression tag

B: 397 - 638 (UniProt: Q99435)

PDB	External Database	Details
Ala 396	-	expression tag
His 639	-	expression tag
His 640	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	39630.7
Branched	Number of molecules	1
	Total formula weight	570.5
Non-Polymers*	Number of molecules	4
	Total formula weight	341.4
All*	Total formula weight	40542.7

*Water molecules are not included.